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Peer Support in Diabetes Management - Insulin Peer Support

Not Applicable
Completed
Conditions
Type 2 Diabetes Treated With Insulin
Interventions
Behavioral: Peer Support
Registration Number
NCT03437525
Lead Sponsor
Shanghai 6th People's Hospital
Brief Summary

This project will develop a combined model of the Shanghai Integration Model and peer support for diabetes self-management with a special focus on appropriate insulin use.

Detailed Description

The development of contemporary diabetes care offers new hope for long and satisfying lives of those with the disease, but also provides increased challenges for integration across the many dimensions of care (varied medications in addition to insulin, specialty services, diet, physical activity, stress management, etc.) and across the many who contribute to care (specialists, primary care providers, nurses, dietitians and patient educators, family members, friends, worksites). The Shanghai Integration Model (SIM) has made great strides to integrating specialty/hospital care with primary/community care. The addition of peer support can enhance patient engagement within that integrated care. Peer support can also integrate care with the daily behaviors and patterns that optimal diabetes management requires and with the family members and others in individuals' daily lives who can support diabetes management.

The "Insulin Peer Support" project is a sub-project of "Peer Support in Diabetes Care", with special focus on appropriate insulin use in the community, to help overcome barriers in insulin treatment and improve treatment compliance. This project will develop a peer support model for diabetes management in Chinese patients undergoing insulin treatment and evaluate its effectiveness in a randomized controlled trial of 10 CHCs in Shanghai.

The project is a collaboration among the Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, the Shanghai Diabetes Institute,the Shanghai Municipal Commission of Health and Family Planning, the Shanghai Centers for Disease Control, and, at the University of North Carolina-Chapel Hill, Peers for Progress, widely recognized for its leadership in promoting peer support in health care and prevention.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
360
Inclusion Criteria
  • Chinese
  • Has type 2 diabetes
  • Receiving treatment at participating community health center
  • Currently using insulin or prescribed insulin but not currently using insulin
Exclusion Criteria
  • Severe mental illness (severe depression, schizophrenia, bipolar disorder, obsessive compulsive disorder, panic disorder, PTSD, borderline personality disorder, etc.)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Peer Support InterventionPeer SupportThe experimental group will receive the peer support intervention for 12 months.
Primary Outcome Measures
NameTimeMethod
Change from Baseline HbA1c at 6 and 12 monthsBaseline, 6 months, 12 months

HbA1c (%)

Secondary Outcome Measures
NameTimeMethod
Change from Baseline Fasting Blood Glucose at 6 and 12 monthsBaseline, 6 months, 12 months

FPG (mmol/L)

Change from Baseline Blood Pressure at 6 and 12 monthsBaseline, 6 months, 12 months

SBP and DBP (mmHg)

Change from Baseline BMI at 6 and 12 monthsBaseline, 6 months, 12 months

Height (cm) and weight (kg)

Change from Baseline Blood Lipids at 6 and 12 monthsBaseline, 6 months, 12 months

Total cholesterol, triglycerides, HDL, LDL (mmol/L)

Change from Baseline Hemoglobin at 6 and 12 monthsBaseline, 6 months, 12 months

Hemoglobin (g/L)

Change from Baseline Red Blood Cell Count at 6 and 12 monthsBaseline, 6 months, 12 months

Red blood cell count (10\^12/L)

Change from Baseline Mean Corpuscular Volume at 6 and 12 monthsBaseline, 6 months, 12 months

Mean Corpuscular Volume (fL)

Change from Baseline Mean Corpuscular Hemoglobin at 6 and 12 monthsBaseline, 6 months, 12 months

Mean Corpuscular Hemoglobin (pg)

Change from Baseline Liver Functioning at 6 and 12 monthsBaseline, 6 months, 12 months

ALT (U/L), AST (U/L), Alkaline phosphatase (U/L), r-GT (U/L)

Change from Baseline Bilirubin at 6 and 12 monthsBaseline, 6 months, 12 months

Total bilirubin (µmol/L), Direct bilirubin (µmol/L)

Change from Baseline Blood Urea at 6 and 12 monthsBaseline, 6 months, 12 months

Blood urea (mmol/L)

Change from Baseline Serum Creatinine at 6 and 12 monthsBaseline, 6 months, 12 months

Serum creatinine (µmol/L)

Change from Baseline Uric Acid at 6 and 12 monthsBaseline, 6 months, 12 months

Uric acid (µmol/L)

Change from Baseline Urine Albumin/Creatinine Ratio at 6 and 12 monthsBaseline, 6 months, 12 months

Albumin (mg/L), Creatinine (mmol/L)

Change in Insulin Functioning at 6 and 12 months6 months, 12 months

Insulin (pmol/L)

Change in C-peptides at 6 and 12 months6 months, 12 months

C-peptide (nmol/L)

Change from Baseline Diabetes Self Care Behaviors at 6 and 12 monthsBaseline, 6 months, 12 months

9 items from Summary of Diabetes Self Care Activities and Behavioral Risk Factor Surveillance System. Items 1-7 measure diabetes self care activities during the previous 7 days. Items 1, 2, 4-7 are assessed on a scale of 0 to 7 days. Item 3 is assessed on scale of 1-4, where 1 represents very low levels of daily activity and 4 represents very high levels of daily activity. Items 8 and 9 are yes/no questions that measure cigarette intake over the past 7 and 30 days.

Change from Baseline Medication Adherence at 6 and 12 monthsBaseline, 6 months, 12 months

Morisky 4-item adherence scale. Four yes/no questions about medication adherence in which yes responses are less favorable. Yes responses are coded as 0, No responses are coded as 1, and scores are summed. A total score of 0 is the lowest level of medication adherence and 4 is the highest level of medication adherence.

Change from Baseline General Quality of Life at 6 and 12 monthsBaseline, 6 months, 12 months

6-item EQ-5D, a standardized instrument for measuring generic health status. The respondents are asked to choose one of the statements which best describes their health status on the surveyed day. Rated level can be coded as a number 1, 2, or 3, which indicates having no problems for 1, having some problems for 2, and having extreme problems for 3. As a result, a person's health status can be defined by a 5-digit number, ranging from 11111 (having no problems in all dimensions) to 33333 (having extreme problems in all dimensions). Item 6 is the visual analogue scale, in which respondents are asked to mark their health status on the day of the interview on a 20 cm vertical scale with end points of 0 and 100, where 0 corresponds to "the worst health you can imagine", and 100 corresponds to "the best health you can imagine"

Change from Baseline Diabetes Quality of Life at 6 and 12 monthsBaseline, 6 months, 12 months

4-item Diabetes Distress Scale, an abbreviated version of the 17-item Diabetes Distress Scale. The respondents are asked to respond to which degree each of the items has bothered them in the past month on a 6-point scale (1-6), where 1 is not a brother and 6 is very bothersome. Scores are summed and divided by 4 to calculate the mean. Mean scores of 3 or higher (moderate distress) are considered worthy of clinical attention.

Change from Baseline Depression at 6 and 12 monthsBaseline, 6 months, 12 months

8-item Patient Health Questionnaire (PHQ), the PHQ-9 minus the last question on suicidal thoughts. The PHQ is a standard instrument used in primary care settings to screen for the presence and severity of depression. The respondents are asked how often they have been bothered by each of the 8 items in the past 2 weeks on a 4 point scale (0-3), where 0 is "not all" and 3 is "nearly every day". The scores for each item are summed to produce a total score between 0 and 24 points. A total score of 0 to 4 represents no significant depressive symptoms. A total score of 5 to 9 represents mild depressive symptoms; 10 to 14, moderate; 15 to 19, moderately severe; and 20 to 24, severe.

Change in Community Support for Diabetes at 6 and 12 months6 months, 12 months

Novel 9-item questionnaire that assesses the degree to which respondents receive community support (other than family) for their diabetes. Items 1-8 are scored from on a scale of 1-5, where 1 is "not at all" and 5 is "completely". Item 9 asks for the relationship of the person / people to the respondent.

Change in Healthcare Utilization at 6 and 12 months6 months, 12 months

Novel 6-item questionnaire that assesses patterns of healthcare and program utilization. Item 1 asks respondents the last time they saw a community health center doctor or nurse for their diabetes. Possible responses are "Within the last 2 weeks", "Within the last month", "Within the last 2 months", "Between 2-4 months ago", and "More than 4 months ago". Items 2-6 ask respondents to recall how many times they accessed healthcare services (peer support, primary care, outpatient hospital care, overnight hospital stays) in the past 3 months. Possible responses are "0", "1-2", "3-5", and "5+".

Change from Baseline Insulin Attitudes at 6 and 12 monthsBaseline, 6 months, 12 months

13-item Chinese Attitudes to Starting Insulin Questionnaire (Ch-ASIQ). Four subscales consisting of 'Self-image and stigmatization' (3 items); 'Factors promoting self-efficacy (5 items); 'Fear of pain or needles' (3 items); and 'Time and family support' (2 items). Responses are scored using a 4-point Likert scale (Totally disagree = 1, Totally Agree = 4). Individual scale scores are calculated by summing the item responses. For the subscales 'Factors promoting self-efficacy' and 'Time and family support', higher scores indicate more positive attitudes towards the use of insulin. For the subscales 'Self-image and stigmatization' and 'Fear of pain or needles' a higher score indicates a more negative attitude towards insulin initiation. The weighted sum of all four scale scores, converting two positively coded scales to negatively coded scales, calculates the overall score with higher scores indicating more negative attitude to starting insulin.

Trial Locations

Locations (11)

Shanghai Sixth People's Hospital

🇨🇳

Shanghai, Shanghai, China

Cao Yang Community Health Center

🇨🇳

Shanghai, Shanghai, China

An Ting Community Health Center

🇨🇳

Shanghai, Shanghai, China

Cao He Jing Community Health Center

🇨🇳

Shanghai, Shanghai, China

Hong Mei Community Health Center

🇨🇳

Shanghai, Shanghai, China

Kang Jian Community Health Center

🇨🇳

Shanghai, Shanghai, China

Tian Lin Community Health Center

🇨🇳

Shanghai, Shanghai, China

Long Hua Community Health Center

🇨🇳

Shanghai, Shanghai, China

Tao Pu Community Health Center

🇨🇳

Shanghai, Shanghai, China

Nan Jing Xi Road Community Health Center

🇨🇳

Shanghai, Shanghai, China

Zhen Ru Community Health Center

🇨🇳

Shanghai, Shanghai, China

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