Clinical Observation of Exosomes in Patients After Q-switched Laser Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- Global Aesthetic Improvement Scale score
研究概览
简要总结
the goal of this half-face controlled study is to evaluate the effect of exosome-containing liquid dressings on the recovery of patients after Nd:YAG laser 532 treatment.
详细描述
The main objective was to collect patients with fleae or seborrheic keratosis after Q-switched laser treatment, and then to use exosomes or matrix on both sides of the face, and finally to evaluate the effect of exosomes on wound healing and prevention of post-inflammatory hyperpigmentation after Nd:YAG laser 532 treatment
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •It meets the diagnostic criteria of seborrheic keratosis or freckle；
- •pepole are able to follow the treatment rules of the study and were followed up for 8 weeks；
- •informed consent
排除标准
- •History of keloids ;
- •Pregnancy or lactation;
- •Any cosmetics containing growth factor-related ingredients used within 6 months prior to treatment
- •Patients with incomplete observation data and incomplete course of treatment were excluded
研究组 & 干预措施
self half face control method
One side of the face was treated with exosome liquid dressing twice a day, and the other side was treated without exosome matrix for 2 weeks. The patients were followed up before treatment and 1, 3，7, 14, 28, and 56 days after treatment
干预措施: Exosome liquid dressing (Drug)
结局指标
主要结局
Global Aesthetic Improvement Scale score
时间窗: 1, 3.5, 7, 14, 28, and 56 days
The treating physician evaluated the patient's improvement, which was divided into four levels: very improved corresponding, substantial improvement, improvement, no change; Corresponding to the best beauty results, significantly improved but not the best, significantly improved, no change
Dermatology Quality of life index
时间窗: 1, 3.5, 7, 14, 28, and 56 days
By answering multiple questions, patients self-rated the impact of their current illness on their lives within a week and scored. The answers were graded on four levels, very serious 3, very serious 2, a little 1, and no 0
次要结局
- post-inflammatory hyperpigmentation(2.4,8 weeks)
研究者
dai jie
Nanjing First Hospital
Nanjing First Hospital, Nanjing Medical University