A clinical trial to compare the effects and dose requirement of the drug - morphine when given through a catheter placed at a higher point in the vertebral column or at a lower point in the vertebral column in patients undergoing upper abdominal surgeries.
Not Applicable
- Conditions
- Health Condition 1: null- Adult patients aged between 18-60 years scheduled for elective upper abdominal surgery under general anesthesia belonging to American Society of Anaesthesiologists (ASA) physical status I and II.
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Patients scheduled for elective upper abdominal surgery under general anesthesia
2) American Society of Anesthesiologists(ASA) physical status I and II
Exclusion Criteria
1) Patient refusal.
2) Known case of Coagulopathy
3) Spine deformities
4) Pregnancy
5) Allergy to morphine or lignocaine
6) History of allergic disorders
7) High risk to develop post-operative nausea and vomiting (Apfel score >3)
8) Inability to comprehend pain score or understand use of PCEA
9) Expected prolonged post-operative ventilation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare the 24 hour Morphine requirement between Thoracic and Lumbar epidural routes to provide adequate post-operative analgesia in patients undergoing upper abdominal surgeries using PCEA.Timepoint: Amount of Epidural Morphine (in milligrams) required by the patient for adequate pain relief in the post operative period. It is estimated at the end of 24 hours in post operative period.
- Secondary Outcome Measures
Name Time Method To assess and compare the incidence of Morphine related side effects which includes pruritus, nausea, vomiting, respiratory depression between the two groupsTimepoint: The number of Morphine related side effects in assessed for a period of 24 hours in post operative period.;To assess and compare the quality of post-operative analgesia of Morphine between the two groups using visual analog scale (VAS) score: at rest (VAS-R) and after coughing (VAS-C)Timepoint: Visual Analog Score (VAS) (Score 1 - 10) is assessed every 1 hour for the first 6 hours in the post operative period and then at 12 hours and 24 hours in the post operative period.