Effects of different forms of coconut on lipid profile

Not Applicable

Completed

• Conditions: ipid profile; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN10859733
• Lead Sponsor: Medical Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-06-08
• Study Start: 2023-09-08
• Last Update Posted: 18 September 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 190

Inclusion Criteria

1. Healthy volunteers aged 25-60 years
2. Total cholesterol level =250 mg/dl
3. Triglyceride level =300 mg/dl
4. Not on any form of medication or on nutritional supplementation

Exclusion Criteria

1. Total cholesterol level =250 mg/dl
2. Triglyceride level =300 mg/dl
3. On any form of medication or nutritional supplementation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Lipid profile (consisting of total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride concentrations) measured at baseline and after 4 and 8 weeks. Lipid profiles were done after 10 hours of mandatory fasting and FBS was done after 8 hours fast.<br>1.1. Total cholesterol, HDL-cholesterol and triglyceride concentrations measured in serum by a Roch/Hitachi Modular P Chemistry Analyzer (Mod P)<br>1.2. The cholesterol assay used the cholesterol oxidase/peroxidase (CHOD/POD) method<br>1.3. HDL cholesterol was measured by a direct non-precipitating method using polyethylene glycol-coupled cholesteryl esterase (PEG-modified enzyme) and cholesterol oxidase<br>1.4. Triglycerides were analyzed using the glycerokinase/glycerophosphate oxidase method after initial hydrolysis with lipoprotein lipase. LDL cholesterol was calculated using the Friedewald formula.

Secondary Outcome Measures

Name	Time	Method
Fasting blood sugar (FBS) and HbA1c measured using Abbott’s Diabetes Care FreeStyle Libre at baseline, after 4 weeks and 8 weeks