Glycemic Response After Palaeolithic-type Meals

Not Applicable

Completed

• Conditions: Glycemic Index of a Meal
• Interventions: Other: Palaeolithic meal 1; Other: Palaeolithic meal 2; Other: Reference meal

• Registration Number: NCT01418573
• Lead Sponsor: Unilever R&D

Brief Summary

The objective of the study is to show post-prandial benefits of Palaeolithic-type meals as compared to a meal constructed along the lines of the WHO dietary recommendations.

Detailed Description

The effects of this set of meals will be assessed with respect to blood

* blood glucose

* plasma insulin

* satiety scores

* plasma gut hormones It is hypothesised that lower post prandial blood glucose concentration, a lower insulin response and increased satiety will be seen after the Palaeolithic meals compared with a reference meal

Study Timeline

• Study Start: 2011-08
• Study First Submitted: 2011-08-16
• Study First Submitted QC: 2011-08-16
• Study First Posted: 2011-08-17
• Primary Completion: 2011-09
• Study Completion: 2011-10
• Status Verified: 2012-02
• Last Update Submitted: 2013-08-12
• Last Update Posted: 2013-08-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 24

Inclusion Criteria

• male
• ≥ 18 and ≤ 60 years old
• Body mass index (BMI) ≥ 18 and ≤ 27.0 kg/m2
• Apparently healthy
• Not smoking
• A fasting blood glucose value within the normal reference value

Exclusion Criteria

• No prescribed medication

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Palaeolithic-type meal 1	Palaeolithic meal 1	-
Palaeolithic-type meal 2	Palaeolithic meal 2	-
The reference meal	Reference meal	-

Primary Outcome Measures

Name	Time	Method
Blood glucose	0-2 hours	positive incremental area under the concentration versus time
Plasma insulin	0-2 hours	net incremental area under the curve
Peak blood glucose	0-2 hours	maximal blood glucose value

Secondary Outcome Measures

Name	Time	Method
Satiety scores	0-2 hours	area under the curve
Gut hormone panel	0-3 hours	Average concentration over time

Trial Locations

Locations (1)

Leatherhead Food Research; 🇬🇧 Leatherhead, Surrey, United Kingdom