Time taken to emerge from anaesthesia after dexmedetomidine or ketamine when used with propofol for anaesthesia in children undergoing urethral surgery
Phase 4
- Conditions
- Health Condition 1: N36- Other disorders of urethra
- Registration Number
- CTRI/2023/06/053761
- Lead Sponsor
- ady Hardinge Medical College and Associated Hospitals
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Male patients in the age group of 3-11yrs
2. ASA I and ASA II
3. Undergoing urethroplasty of duration 1-4 hours
Exclusion Criteria
1.Any known allergy to drugs used in the study
2.Patients with language barrier/ mental retardation/ unable to communicate
3.Indication for use of opioids during surgery.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of time taken (in minutes) to achieve modified Aldrete score of � 9 [Mean ± SD or median (IQR)] using propofol either with ketamine or dexmedetomidine in children undergoing urethroplasty.Timepoint: Immediate postoperative period
- Secondary Outcome Measures
Name Time Method Comparison between the groups <br/ ><br>1.Mean plasma concentration of propofol (µg/ml) <br/ ><br>2.Mean propofol requirement (µg/kg /min) <br/ ><br>3. Mean difference between awake time predicted by the TCI pump & actual awake time <br/ ><br>4. Mean total 24 hours post-operative analgesic requirement <br/ ><br>5. Proportion of patients with occurrence of post-operative nausea & vomiting, irrelevant talk, hallucination, occurrence of explicit recall and haemodynamic complications (bradycardia, tachycardia, hypotension and hypertension)Timepoint: 1.Immediate postoperative period <br/ ><br>2.Immediate postoperative period <br/ ><br>3. Immediate postoperative period <br/ ><br>4. 24 hours <br/ ><br>5. 24 hours