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临床试验/NCT03864809
NCT03864809Unknown不适用

• Sleep Disturbance Among Patients With Psoriasis and Atopy and Comparison Between Them

Assiut University0 个研究点目标入组 150 人开始时间: 2019年6月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
150
主要终点
severity of the psooriasis (Psoriasis Area and Severity Index)

研究概览

简要总结

Comparison between sleep disturbance in atopy and psoriasis and control

详细描述

Sleep is essential for daytime functioning and health and important for both psychological and physiological wellbeing . A growing body of research indicates that chronic sleep disturbance is associated with impaired quality of life (QoL) and a risk factor for poorer health, for example depression cardiovascular disease, hypertension 1 and diabetes.

insomnia, the most common sleep disorder, is a clinical condition defined as difficulties falling asleep and/or maintaining sleep and/or poor sleep quality despite adequate opportunity for sleep resulting in significant daytime impairment.

The development of insomnia in healthy populations has a bi-directional relationship with psychological factors such as anxiety, depressive symptoms and stress, and may in clinical populations also be associated with physical symptoms, such as pain. the physical symptoms in psoriasis, such as itch, one would expect a higher prevalence of sleep disturbance in this patient group. On the other hand Sleep disturbance is common also in patients with atopic dermatitis (AD). Patients with AD often have sleep disturbances due to pruritus.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients with Psoriasis and Patients with A topic dermatitis

排除标准

  • All patient have another dermatological disease

结局指标

主要结局

severity of the psooriasis (Psoriasis Area and Severity Index)

时间窗: 1 hour

calculation of the severity through questionaire , 0 = None 1. = Slight 2. = Moderate 3. = Severe 4. = Very severe

次要结局

  • 2.HRQoL (Dermatology Life Quality Index);(1 hour)
  • .insomnia severity [Insomnia Severity Index (ISI)];(1 hour)
  • sleep quality [Pittsburgh Sleep Quality Index (PSQI)];(1 hour)
  • stress (Perceived Stress Scale);(1 hour)
  • itch (Itch Severity Scale);(1 hour)
  • and depressive symptoms (Beck Depression Inventory(1 hour)
  • severity of a topic dermatitis(1 hour)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amani Mahmoud Abdelmohsen

Principal Investigator

Assiut University

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