Assessing Adolescent Use of Nexplanon Over Time

Active, not recruiting

• Conditions: Contraception
• Interventions: Behavioral: Contraceptive use (continuation/switching/discontinuation)

• Registration Number: NCT04889079
• Lead Sponsor: University of Utah

Brief Summary

The purpose of this study is to compare Nexplanon decision-making, uptake, satisfaction and contraceptive outcomes (continuation, switching, discontinuation) over a 12-month period among adolescents ages 15-18 to adolescents ages 19-24, living in Utah. Data from this study will provide valuable information for clinical and public health offerings, counseling and support for Nexplanon use across stages of adolescence.

Detailed Description

Despite increasing availability of Nexplanon in the United States, only limited resesarch exists on Nexplanon use among adolescents, particularly nulliparous adolescents. A Cochrane systematic review of long-acting contraception use among adolescents in 2017 identified only four studies that had specifically assessed implant use and continuation among adolescents \[1\]. Of these, the majority of studies assessed use postpartum \[1\]. The majority of research on adolescent attitudes around and barriers to long-acting reversible contraception has been conducted on intrauterine devices, rather than implants, and further research is needed to understand decision-making and behaviors around implant use \[2\]. Additionally, no studies have assessed differences in adolescent decision-making by age. While adolescence is considered ages 10-24 \[3\], this period is one of substantial change, physically, mentally, and in stages of life. Contraceptive use can be influenced by all of these \[4\] and understanding differences in stages of adolescence could result in meaningful differences in counseling and support approaches.

The purpose of this study is to compare Nexplanon decision-making, uptake, satisfaction and contraceptive outcomes (continuation, switching, discontinuation) over a 12-month period among adolescents ages 15-18 to adolescents ages 19-24, living in Utah. Data from this study will provide valuable information for clinical and public health offerings, counseling and support for Nexplanon use across stages of adolescence.

Study Timeline

• Study First Submitted: 2021-05-11
• Study First Submitted QC: 2021-05-11
• Study First Posted: 2021-05-17
• Study Start: 2021-06-06
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-07
• Last Update Posted: 2024-05-08
• Primary Completion: 2024-12-31
• Study Completion: 2025-05-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Female
• Target Recruitment: 255

Inclusion Criteria

• Between the ages of 15-24;
• Not currently pregnant;
• Planning to avoid pregnancy for the next 12 months;
• Selecting the contraceptive implant as their contraceptive method of choice;
• Willing to be contacted via email survey 4 times over 12-months

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Adolescent females, aged 15-18	Contraceptive use (continuation/switching/discontinuation)	Adolescents females aged 15-18, who selected a contraceptive implant to prevent pregnancy.
Adolescent females, aged 19-24	Contraceptive use (continuation/switching/discontinuation)	Adolescents females aged 19-24, who selected a contraceptive implant to prevent pregnancy.

Primary Outcome Measures

Name	Time	Method
12-month contraceptive outcomes	12-months	This outcome measures contraceptive use. The question asks "are you still using the Nexplanon implant that you received", and then the outcomes are either: continuation, switching or discontinuation.

Secondary Outcome Measures

Name	Time	Method
Contraceptive satisfaction	12-months	The 5-point Likert satisfaction scale asks "how satisfied are you with your Nexplanon implant?" and the scale ranges from 1-Very unsatisfied to 5-Very satisfied.

Trial Locations

Locations (1)

University of Utah; 🇺🇸 Salt Lake City, Utah, United States