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A study to evaluate the safety and efficacy of Nutricharge Glycem Tablet administered with Nutricharge Glycem Prodiet in Pre-diabetic subjects

Phase 4
Conditions
Health Condition 1: null- Pre Diabetic Subjects
Registration Number
CTRI/2017/10/010007
Lead Sponsor
Trophic Wellness Private Limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1)Willing and able to understand and provide written informed consent.

2) Male or Female aged 18 years and older

3) Random blood glucose level between 140 to 200mg/dL

4) Eligible participants must not be diagnosed with Type 1 or Type 2 diabetes

5) Being mentally competent and able to understand all study requirements.

6) General medical condition does not interfere with trial procedures (at investigator discretion)

7) Females are eligible if:

A. They do not plan to become pregnant during the study

B. Negative screening pregnancy test

C. Sexually active women, unless surgically sterile or post menopausal, must use one of the following methods to avoid pregnancy during the study: 1. Abstinence from penile/vaginal intercourse during the study; 2. Double barrier contraceptive methods 1 of which must be condom.

Exclusion Criteria

1. Known hypersensitivity to the Investigational Product

2. Lactose intolerance

3. Unable to perform low impact physical activity, such as being chair-bound or

having low mobility;

4. Being unable to chew and digest food normally and to eat a balanced diet

(e.g. any digestive disease)

5. Type 1 and Type 2 Diabetic patients

6. Subjects taking Hypoglycaemic medication/s

7. Subjects positive for hepatitis B, Hepatitis C, HIV 1 & 2, VDRL or active

autoimmune disorders.

8. In subjects with hepatic impairment. Having clinically significant ALT. AST

bilirubin levels at screening.

9. Serious underlying diseases or disorder and complications that may interfere

for assessment of the efficacy and safety of the Investigational Productas perthe discretion of the Investigator.

10. Any clinically significant abnormal laboratory parameter evaluated duringscreening.

11. Current use of nutritional supplements and or medical foods within 30 daysprior to the beginning of the study and for the duration of the study.

12. Use of prescription medications and/or nonprescription medications for acutemedical conditions, semi-acute medical conditions and weight loss.

13. Female subjects who are currently pregnant and/or breast feeding.

Study & Design

Study Type
PMS
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome measure is to assess the change in Random Blood glucose level from baseline to day 90 in pre-diabetic subjects.Timepoint: Day 90
Secondary Outcome Measures
NameTimeMethod
The secondary outcome measures are <br/ ><br>1. To monitor Adverse Events/Serious Adverse Events (SAE) (including <br/ ><br>laboratory variables) occurrence <br/ ><br>2. Stark QOL (Overall health status)assessment on day 30, 60 and 90 <br/ ><br>Timepoint: Day 90
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