Comparing the effect of Therapeutic Doses of 200 and 50000 Units of Vitamin D on Serum 25(OH)D Levels in Pregnant Women Referred to Shahid Sayyad Shirazi Hospital of Gorgan between 2013-14
Phase 2
- Conditions
- Vitamon D Deficiency.Vitamin D Dificiency
- Registration Number
- IRCT2014121120276N1
- Lead Sponsor
- Gorgan Congenital malformations research center, Golestan University of Medical Sciences,Gorgan, Ira
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
Inclusion criteria included gestational age 12-16 weeks based on first trimester ultrasound or accurate LMP; nulliparity; singleton pregnancy; vitamin D deficiency. Exclusion criteria included incomplete treatment of supplements or impossible follow-up; a history of high-risk pregnancy; a history of parathyroid disease; hypocalecemia or hypercalcemia; underlying disease such as liver disease, renal disease; hypertension and malabsorption disorders (based on medical history or personal statements); diabetes (based on routine tests done during pregnancy).
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficacy of different doses of vitamin D supplements and treatment of vitamin D deficiency in pregnant women. Timepoint: 20 weeks after intervention. Method of measurement: Measurement of serum levels of 25 (OH) D in ng/dl.
- Secondary Outcome Measures
Name Time Method Prevention of maternal and neonatal complications of pregnancy. Timepoint: 20 weeks after intervention. Method of measurement: Evaluation on term delivery in terms of complications.;Safety of treatment with vitamin D supplement. Timepoint: 20 weeks after intervention. Method of measurement: Evaluation on term delivery in terms of hypervitaminosis and drug side effects.