Open Sinus Lift Technique With Simultaneous Implantation Using Platelet Rich Fibrin (PRF) Versus Nano-crystalline Hydroxyapatite

Not Applicable

• Conditions: Atrophied Posterior Maxillary Ridge
• Interventions: Procedure: Evaluation of bone quantity in open sinus lift technique with simultaneous implantation ( Nano crystalline hydroxyapatite); Procedure: Evaluation of bone quantity in open sinus lift technique with simultaneous implantation (PRF)

• Registration Number: NCT02577289
• Lead Sponsor: Cairo University

Brief Summary

Evaluation of bone quantity in open sinus lift technique with space maintaining using platelet rich fibrin (PRF) as sole augmentation material versus nano crystalline hydroxyapatite with simultaneous placing of implants.

Detailed Description

Evaluation of bone quantity in open sinus lift technique with simultaneous implantation using platelet rich fibrin (PRF) versus Nano-crystalline Hydroxyapatite as sole grafting material in patients with atrophied posterior maxillary ridge which provides a new modality for treatment of patients with atrophied posterior maxillary ridge with least cost and a much easier way using platelet rich fibrin (PRF) as substitution to bone graft

Study Timeline

• Study Start: 2015-07
• Status Verified: 2015-10
• Study First Submitted: 2015-10-13
• Study First Submitted QC: 2015-10-14
• Last Update Submitted: 2015-10-14
• Study First Posted: 2015-10-16
• Last Update Posted: 2015-10-16
• Primary Completion: 2017-10
• Study Completion: 2017-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• All patients should be seeking for implant supported prosthesis in posterior maxilla bilaterally
• All patients should have atrophied posterior maxillary ridge with the maximum height of the alveolar bone is from 3 mm to 5 mm

Exclusion Criteria

• Ongoing steroid therapy;
• Uncontrolled diabetes;
• Recent cardiovascular diseases;
• Inflammation of the maxillary sinus;
• Previous radiant therapy for neoplastic pathologies
• Patient who have had previous failed sinus augmentation, or exhibited pathological finding or had a history of maxillary sinus disease or operations or whose medical condition might increase surgical risk of the research protocol were excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group ( Hydroxyappetite)	Evaluation of bone quantity in open sinus lift technique with simultaneous implantation ( Nano crystalline hydroxyapatite)	Patients will undergo open sinus lift using nano crystalline hydroxyapatite as augmentation material and placing implants simultaneously then evaluation of bone quantity in open sinus lift technique with simultaneous implantation ( Nano crystalline hydroxyapatite)
Test group (PRF)	Evaluation of bone quantity in open sinus lift technique with simultaneous implantation (PRF)	Patients will undergo open sinus lift using PRF as sole augmentation material and placing implants simultaneously then Evaluation of bone quantity in open sinus lift technique with simultaneous implantation (PRF)

Primary Outcome Measures

Name	Time	Method
The amount of new bone formation the sinus cavity using CBCT	6 months	the amount of new bone formation of PRF in comparison with Nano-crystalline hydroxyappetite in millimeters using cone beam computed tomography (CBCT)

Trial Locations

Locations (1)

Faculty of oral and dental medicine; 🇪🇬 Cairo, Egypt