Can Face Masks Reduce Transmission of SARS-CoV-2 in Bangladesh? A Cluster Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 350,000
- 试验地点
- 2
- 主要终点
- Symptomatic SARS-CoV2 infection
研究概览
简要总结
The primary goal of the village-level intervention is to assess whether mask-wearing reduces community-level COVID-19 seroconversion. The individual experiment assess whether masks protect against COVID-19 seroconversion. It also assesses the efficacy of high-quality cloth vs. surgical masks.
详细描述
This study intends to answer the following research questions:
Can mask distribution and mask promotion at homes, mosques, markets and other public areas successfully change community mask-wearing norms to increase mask-wearing?
Can community mask-wearing reduce COVID-19 seroconversions?
Can mask wearing reduce COVID-19 seroconversions for the wearer?
Are high-quality cloth or "surgical" masks more effective in reducing COVID-19 seroconversions?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
盲法说明
The intervention involves wearing a face mask so participants will know if they are in the intervention group. The investigators will be blinded as to intervention assignment.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Community experiment: Live in selected village
- •Individual experiment: Work in selected market
排除标准
- 未提供
结局指标
主要结局
Symptomatic SARS-CoV2 infection
时间窗: 12 weeks
Symptomatic SARS-CoV2 infection, assessed via antibody testing 12 weeks after baseline, among individuals who report symptoms consistent with COVID-19 at 5 weeks or 9 weeks after baseline
次要结局
- Observed prevalence of proper mask wearing(intervention weeks 0, 1, 2, 4, 6, 8, and 12 in the community experiment and intervention weeks 0, 1, 2, 4, and 6 in the individual experiment)
- SARS-CoV2 infection(12 weeks)
- Respiratory infection prevalence(5 and 9 weeks)