Rebound Pain and Related Factors in Postoperative Patients With Total Knee Arthroplasty

Recruiting

• Conditions: Postoperative Complications; Postoperative Nausea and Vomiting; Postoperative Pain

• Registration Number: NCT05910281
• Lead Sponsor: Gulhane Training and Research Hospital

Brief Summary

The aim of this prospective observational study is to detect rebound pain and related factors in postoperative patients with total knee arthroplasty.

Detailed Description

Total knee arthroplasty is an effective treatment method for knee osteoarthritis and because it is an invasive method, more than 50% of patients experience postoperative pain. Peripheral nerve blocks are widely used for optimal pain control. The femoral block is a frequently preferred peripheral nerve block method for postoperative analgesia in total knee arthroplasty surgery. However, after peripheral nerve block, a condition called rebound pain (rebound pain), which is described as very severe pain, lasting about 2 hours, usually of the burning type, occurs. The aim of this prospective observational study is to detect rebound pain and related factors in postoperative patients with total knee arthroplasty.

Study Timeline

• Study First Submitted: 2023-06-09
• Study First Submitted QC: 2023-06-16
• Study First Posted: 2023-06-18
• Status Verified: 2023-07
• Study Start: 2023-07-01
• Last Update Submitted: 2023-07-21
• Last Update Posted: 2023-07-24
• Primary Completion: 2024-12-01
• Study Completion: 2025-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• 18-80 years older age who underwent total knee arthroplasty

Exclusion Criteria

• ASA score 4 or >4
• Active infection
• End stage organ failure
• Pregnancy
• Established diagnosis neuropsychiatric disease ( epilepsy, neuropathy, neuromuscular disease, cerebrovascular disease...)
• Uses of oral corticosteroids

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual Analogue Scale	postoperative 3-5 days fellow-up	The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be').

Trial Locations

Locations (1)

Ankara City Hospital; 🇹🇷 Ankara, None Selected, Turkey