Improving Risk Stratification of Emergency Department Patients With Acute Heart Failure
- Conditions
- Heart Failure
- Registration Number
- NCT06065761
- Lead Sponsor
- Kaiser Permanente
- Brief Summary
The primary goal is to build and test a previously developed and validated risk model and clinical decision support tool embedded within the electronic health record to improve risk stratification of emergency department (ED) patients with acute heart failure (AHF).
- Detailed Description
The study team will build an electronic health record-embedded clinical decision support tool using a recently developed risk prediction model that curates patient-specific data in real-time, accurately estimates short-term patient risk, and presents tailored clinical recommendations. This will be a regional implementation study in which the tool is turned on at 21 emergency departments (ED) across Kaiser Permanente Northern California (KPNC). The study team will validate risk predictions and study key clinical outcomes as part of this trial.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 17459
- Adult (≥18y) KPNC members treated in the ED for presumed acute heart failure
- Children (<18y).
- Patients who left against medical advice or eloped prior to ED physician evaluation.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of patients with serious adverse events 30 days from index ED visit Serious adverse events include mortality, cardiopulmonary resuscitation (CPR), intubation/ventilation, new end-stage renal disease (ESRD), balloon pump placement, or percutaneous coronary intervention (PCI)/coronary artery bypass grafting (CABG)
Number of patients with all-cause mortality 30 days from index ED visit
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (21)
Kaiser Permanente Fresno Medical Center
🇺🇸Fresno, California, United States
Kaiser Permanente Redwood City Emergency Department
🇺🇸Redwood City, California, United States
Kaiser Permanente San Francisco Emergency Department
🇺🇸San Francisco, California, United States
Kaiser Permanente Santa Rosa Emergency Department
🇺🇸Santa Rosa, California, United States
Kaiser Permanente Vacaville Medical Center
🇺🇸Vacaville, California, United States
Kaiser Permanente Antioch Emergency Department
🇺🇸Antioch, California, United States
Kaiser Permanente San Jose Emergency Department
🇺🇸San Jose, California, United States
Kaiser Permanente San Leandro Emergency Department
🇺🇸San Leandro, California, United States
Kaiser Permanente Vallejo Medical Center
🇺🇸Vallejo, California, United States
Kaiser Permanente Santa Clara Emergency Department
🇺🇸Santa Clara, California, United States
Kaiser Permanente Fremont Emergency Department
🇺🇸Fremont, California, United States
Kaiser Permanente South Sacramento Emergency Department
🇺🇸Sacramento, California, United States
Kaiser Permanente Sacramento Emergency Department
🇺🇸Sacramento, California, United States
Kaiser Permanente Manteca Medical Center
🇺🇸Manteca, California, United States
Kaiser Permanente Richmond Emergency Department
🇺🇸Richmond, California, United States
Kaiser Permanente Modesto Medical Center
🇺🇸Modesto, California, United States
Kaiser Permanente Oakland Emergency Department
🇺🇸Oakland, California, United States
Kaiser Permanente Roseville Emergency Department
🇺🇸Roseville, California, United States
Kaiser Permanente San Rafael Emergency Department
🇺🇸San Rafael, California, United States
Kaiser Permanente Walnut Creek Medical Center
🇺🇸Walnut Creek, California, United States
Kaiser Permanente South San Francisco Emergency Department
🇺🇸South San Francisco, California, United States