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Clinical Trials/NCT04869462
NCT04869462
Completed
Not Applicable

Prospective, Monocentric, Single Arm, Observational PMCF - Study on the Performance and Safety of Double-Shank Titanium Ligation Clip in Urology (Prostatectomy and Nephrectomy)

Aesculap AG1 site in 1 country67 target enrollmentMay 27, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Prostate Cancer
Sponsor
Aesculap AG
Enrollment
67
Locations
1
Primary Endpoint
Rate of slippage / movement of the clip in relationship to the total number of used clips.
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Prospective, monocentric, single arm, observational PMCF - Study on the Performance and Safety of Double-Shank Titanium Ligation Clip in Urology (Prostatectomy and Nephrectomy)

Detailed Description

The objective of this observational study is to collect systematically and proactively data regarding the Aesculap® DS Titanium Ligation Clip under daily clinical practice when used in urology in different indications. The hypothesis of this study is that this event, slippage / movement of the clip, is extremely rare through the design if used in accordance with the Instructions for Use (IfU). The observed rate through the total number of clips might be a valuable parameter and could influence future research. Furthermore, this study is one of the PMCF measures which enable the manufacturer to monitor the safety and performance of the Aesculap® DS Titanium Ligation Clips. The products bear the CE-marking and are routinely used within this institution for the above-mentioned procedures.

Registry
clinicaltrials.gov
Start Date
May 27, 2021
End Date
January 29, 2022
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Planned Da Vinci radical prostatectomy using DS Titanium Ligation Clips (according to the IfU) - OR
  • Planned laparoscopic nephrectomy using Titanium Ligation Clip (according to the IfU) - OR
  • Planned Da Vinci partial nephrectomy using Titanium Ligation Clip (according to the IfU)
  • Patient's written informed consent
  • Age ≥ 18 years
  • Intraoperative Usage of DS Titanium Ligation Clips (according to the IfU)

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Rate of slippage / movement of the clip in relationship to the total number of used clips.

Time Frame: Intraoperatively

Slippage / movement of the Aesculap® DS Titanium Ligation Clip is an observable slippage, movement, or rotation after the clip was successfully applied and the application forceps was removed. The number of observed slippage / movement of the clip will be documented on the CRF, the clip size, step of the procedure and further measures were necessary, i.e. removal of the clip or application of another clip, will be documented. In the end the rate will be brought in relationship to the overall number of applied clips. Thus, the number of applied clips is documented, for each clip size.

Secondary Outcomes

  • Rate of Adverse events (intra- and postoperative)(up to discharge from hospital (approximately 10 days post surgery))

Study Sites (1)

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