跳至主要内容
临床试验/NCT01080430
NCT01080430已完成不适用

Short-term and Long-term Effects of the Rotational Maneuver in Patients With Chronic Vestibular Imbalance

Day General Hospital.2 个研究点 分布在 2 个国家目标入组 16 人开始时间: 2007年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
16
试验地点
2
主要终点
Directional preponderance (DP)

研究概览

简要总结

Rotational maneuver is a vestibular rehabilitation method, performed in a supervised manner. Using a rotating chair, subjects are rotated towards the opposite direction of dominant side in order to inhibit this side and simultaneously, stimulate the subordinate side. We propose that the rehabilitative effect is the result of a decrease in the vestibular imbalance, mainly due to a decrease in the response of the dominant vestibular side. Previously, we have shown the short-term effects of this maneuver on patients with recent onset vestibular imbalance. In the present study, we investigated the long-term effects of the rotational maneuver in patients with a history of peripheral vestibular vertigo for at least one year, originally confirmed by clinical tests. Our results show a significant improvement which lasted for >4 weeks after the end of rehabilitation (i.e., the last time tested). Moreover, there seems to be a relationship between the decrease in DP values and a decrease in subjective symptoms. We propose that this maneuver can be used as an effective method for both short- and long-term rehabilitation.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Supportive Care
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • History of vertigo for at least one year
  • Not under drug therapy for vertigo
  • directional preponderance >10% measured by electronystagmography during rotation test

排除标准

  • severe vertigo
  • intolerance to rotation
  • previously diagnosed for a central pathology (e.g., neuroma)
  • previously diagnosed with a fluctuating vestibular disorder (e.g., Menier's)

结局指标

主要结局

Directional preponderance (DP)

时间窗: Every 3-7 days for one month

It provides an objective measure of vestibular asymmetry (percentage) in response to rotation. Eye movements are measured by electronystagmography during head rotations to the right and to the left. DP (%) is calculated by the equation: 100 x (max eye velocity for rightward rotations - max eye velocity for left rotations) / (max eye velocity for rightward rotations + max eye velocity for left rotations). Values below 10% are considered normal.

次要结局

  • Subjective sense of a decrease in imbalance and dizziness.(every 3-7 days for one month)

研究者

发起方
Day General Hospital.
申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr Nayer Rassaian

Professor / Doctor

Shahid Beheshti University of Medical Sciences

研究点 (2)

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