To compare safety and efficacy of propranolol with flunarizine in adult patients suffering from migraine as prophylactic drugs.
- Conditions
- Health Condition 1: G438- Other migraine
- Registration Number
- CTRI/2023/06/053593
- Lead Sponsor
- Dr. Rajendra Prasad Government Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1) Patients willing to give consent.
2) Male and female outpatients between 18-65 years of age with documented history of
migraine (with or without aura) acc. to HIS criteria.
3) Duration of at least 3 months.
4) Frequency of two or more migraine headache per month.
5) Currently not on any prophylactic medication in the last 1 month.
6) Patientsâ?? ability to fill a reliable headache diary successfully.
1) Patients refusing to give consent.
2) <18 or >65 of age with non-migrainous headache.
3) Pregnant and Lactating women.
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4) Patients with h/o asthma, diabetes, renal, cardiovascular, liver, neoplastic disease,
neurological and mental disorders are excluded.
5) Active alcohol users.
6) Patients allergic or with known contraindications to any of study drugs.
7) Patients who have already taken either of the above-mentioned migraine prophylactic
drugs.
8) Previous unresponsiveness to more than two antimigraine prophylactic drugs.
9) NCCT Head suggesting of any other disease except migraine i.e., abnormal fundus etc.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method reduction in frequency intensity and severity of migraine attacksTimepoint: at baseline at 4 weeks and at 8 weeks from date of enrollment
- Secondary Outcome Measures
Name Time Method to evaluate safety profile to both drugsTimepoint: at baseline at 4 weeks and at 8 weeks from date of enrollment