Characterising ocular blood flow changes with an exercise stimulus using optical coherence tomography angiography (OCT-A) in healthy, normal tension glaucoma and diabetic retinopathy patients.

niversity of NSW, Rural Clinical School0 个研究点目标入组 27 人开始时间: 2020年8月24日最近更新: 2022年6月27日

适应症

试验速览

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•Participation will be offered to patients aged between 18-75 years who attend the Port Macquarie Eye Centre (PMEC).
•* Healthy controls: patients who attend the clinic for treatment of non-glaucomatous and non-diabetic issues.
•* Normal tension glaucoma patients: normal tension glaucoma diagnosed by treating ophthalmologist with a peak IOP <21mmHg.
•* Diabetic retinopathy patients: patients with diabetic retinopathy of ICDRSS grade mild or moderate without diabetic macular oedema.

•* Inability to provide informed consent/assent
•* Inability to sit at OCT/A
•* Hand pathology: chronic hand pain due to any cause, broken skin on the palm or fingers, Rheumatoid Arthritis, hand surgery in the last 3 months
•* Ocular pathology: cataracts of nuclear sclerotic grade >2+, refraction spherical equivalent < -3D or > +3D, prior corneal surgery or significant corneal disease, prior glaucoma drainage surgery, cataract surgery within the last 3 months
•* Current known pregnancy
•* Potentially vasoactive systemic or topical medications: blood pressure treatment particularly beta-blockers, calcium channel blockers, or alpha agonists

发起方

niversity of NSW, Rural Clinical School