MedPath

Misoprostol Before and After Cesarean Section

Phase 3
Conditions
Post Partum Hemorrhage
Interventions
Registration Number
NCT03463070
Lead Sponsor
sarah mohamed hassan
Brief Summary

comparison of the effect of misoprostol before and after cesarean on the blood loss

Detailed Description

70 women who received 600 mg misoprostol rectally preoperatively versus 70 women who received 600 mg misoprostol postoperatively at operating theatre

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
140
Inclusion Criteria
  • Women not in active labor have reactive non-stress test.
  • No contraindications to prostaglandins.
  • Have no history of coagulopathy.
Exclusion Criteria
  • Placenta previa.
  • Maternal hypertension.
  • Diabetes mellitus.
  • Previous CS and those with active labor.
  • Multiple Fibroid uterus.
  • Multiple pregnancies or polyhydramnios.
  • Previous myomectomy, previous history of PPH.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
postoperative misoprostol grouprectal misoprostol 600mg70 women who received 600 mg misoprostol postoperatively at operating theatre after cesarean section
preoperative misoprostol grouprectal misoprostol 600mg70 women who received 600 mg misoprostol rectally preoperatively before cesarean section
Primary Outcome Measures
NameTimeMethod
postoperative blood lossevery 6 hours during first 24 hours.

weighing the soaked napkins after collection of soaked towel

intraoperative blood lossthe operation time

Difference in weight of linen towels (gm)+Volume of contents of suction bottle (ml)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Kasr El Ainiy Hospital

🇪🇬

Cairo, Egypt

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