The Effect of Misoprostol Given Preoperative Versus Postoperative on Blood Loss With Elective Cesarean Section: Randomized Controlled Trial
试验速览
- 阶段
- 3 期
- 发起方
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- postoperative blood loss
研究概览
简要总结
comparison of the effect of misoprostol before and after cesarean on the blood loss
详细描述
70 women who received 600 mg misoprostol rectally preoperatively versus 70 women who received 600 mg misoprostol postoperatively at operating theatre
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women not in active labor have reactive non-stress test.
- •No contraindications to prostaglandins.
- •Have no history of coagulopathy.
排除标准
- •Placenta previa.
- •Maternal hypertension.
- •Diabetes mellitus.
- •Previous CS and those with active labor.
- •Multiple Fibroid uterus.
- •Multiple pregnancies or polyhydramnios.
- •Previous myomectomy, previous history of PPH.
研究组 & 干预措施
postoperative misoprostol group
70 women who received 600 mg misoprostol postoperatively at operating theatre after cesarean section
干预措施: rectal misoprostol 600mg (Drug)
preoperative misoprostol group
70 women who received 600 mg misoprostol rectally preoperatively before cesarean section
干预措施: rectal misoprostol 600mg (Drug)
结局指标
主要结局
postoperative blood loss
时间窗: every 6 hours during first 24 hours.
weighing the soaked napkins after collection of soaked towel
intraoperative blood loss
时间窗: the operation time
Difference in weight of linen towels (gm)+Volume of contents of suction bottle (ml)
次要结局
未报告次要终点
研究者
sarah mohamed hassan
lecturer of obstetrics and gynecology
Kasr El Aini Hospital