ltra-early tranexamic acid after subarachnoid hemorrhage.
- Conditions
- subarachnoid hemorrhageintracerebral hemorrhagesubarachnoidale bloedinghersenbloeding
- Registration Number
- NL-OMON22386
- Lead Sponsor
- Academic Medical CenterMeibergdreef 91105 AZ AmsterdamTel: 020-5666564Fax: 020-5669590
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 950
Inclusion Criteria
1. Admission to one of the study centers or their referring hospitals;
2. CT-confirmed SAH with ictus less than 24 hours ago;
Exclusion Criteria
1. No loss of consciousness after the hemorrhage with WFNS grade 1 or 2 on admission in combination with a perimesencephalic hemorrhage;
2. Bleeding pattern on CT compatible with a traumatic SAH;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Modified Rankin Scale score dichotomized as a favourable (0-3) or unfavourable (4-6) outcome.
- Secondary Outcome Measures
Name Time Method 1. Case fatality rate;<br /><br>2. Cause of poor outcome;<br /><br>3. Rebleed rate;<br /><br>4. Thromboembolic complications;<br /><br>5. Delayed cerebral ischemia rate;<br /><br>6. Complications (hydrocephalus, thromboembolic events, extracranial thrombosis or hemorrhagic complications);<br /><br>7. Care costs.