Investigating Variation in Hospital Acute Coronary Syndrome Outcomes

Completed

• Conditions: Acute Myocardial Infarction

• Registration Number: NCT01808027
• Lead Sponsor: University of Leeds

Brief Summary

To investigate the causes of hospital variation in outcomes from acute coronary syndromes in England and develop recommendations for improving patient care.

Detailed Description

Over the last few years the chance of dying from a heart attack in England and Wales has reduced dramatically. Even so, there remain huge differences in mortality between hospitals. For example, up to a third of patients with a heart attack who attend hospitals in England are more likely to die than would be expected. That is, the type of treatment and the risk of death depends upon where a patient lives and which hospital they attend. In part, the variation in death may be due to the services available at the hospital or to factors such as socioeconomic deprivation. It may also relate to other factors such as depression, cardiac rehabilitation and whether patients take their medication after discharge from hospital. Using powerful statistical approaches that include measures of quality of life, we propose to examine data about heart attacks in England and investigate the 'postcode lottery of care'. Our aim, using regional data about heart attacks is to identify and measure the effects of hospital care. This research will identify hospital qualities that promote improved patient care. In doing so, best practice will be highlighted and healthcare policy changed so that all patients will have an equal chance of surviving a heart attack.

Study Timeline

• Study Start: 2011-02
• Primary Completion: 2013-02
• Study Completion: 2013-02
• Status Verified: 2013-03
• Study First Submitted: 2013-03-07
• Study First Submitted QC: 2013-03-07
• Last Update Submitted: 2013-03-07
• Study First Posted: 2013-03-08
• Last Update Posted: 2013-03-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 5555

Inclusion Criteria

• Age > 18 years
• Both sexes
• Acute admission to the acute Trust with suspected acute coronary syndrome

Exclusion Criteria

• Patients at a terminal stage of any illness
• Those in whom follow up would be inappropriate or impractical

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
delays to treatment	12 months	Quantification of hospital attributable effects relating to early and late mortality

Secondary Outcome Measures

Name	Time	Method
Describing trajectories of quality of life recovery patterns	12 month	Describing trajectories of quality of life recovery patterns

Trial Locations

Locations (1)

University of Leeds; 🇬🇧 Leeds, West Yorkshire, United Kingdom