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Cardiopulmonary Rehabilitation for Post-acute COVID-19 Symptoms

Not Applicable
Completed
Conditions
Cardiopulmonary
Interventions
Other: Exercise programme
Registration Number
NCT05787353
Lead Sponsor
Eskisehir City Hospital
Brief Summary

The purpose of this RETROSPECTIVE study was to compare the effect of a hospital and home-based cardiopulmonary rehabilitation (CPR) program on exercise endurance and quality of life in post-acute COVID-19 patients.

88 post-acute COVID-19 patients were divided two groups according to receiving hospital (n=45) or home-based CPR (n=43)in our rehabilitation clinic between January and July 2021. Both protocols consisted of aerobic, breathing and flexibility exercises. Hospital-based CPR: three or four days per week for a total of 20 sessions. Home-based CPR: three or four days/a week over a period of six weeks. The results of six meters walk test (6MWT) for exercise endurance as a main outcome measure, and Borg-dyspnea/fatigue, the visual analog scale (VAS) for pain and the Short Form-36 (SF-36) as secondary outcome measures before and after treatment were recorded.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
88
Inclusion Criteria
  • being 18 years or older
  • having COVID-19 treatment (home quarantine/hospital/intensive care unit) according to a positive polymerase chain reaction (PCR) test in a nasopharyngeal + oropharyngeal swab or chest computed tomography (CT)
  • participating in a home-based exercise program (for 6 weeks) or hospital-based CPR (for 12-20 sessions) due to post-acute COVID-19 symptoms (fatigue, myalgia, dyspnea).
Exclusion Criteria
  • Patients who had both a negative PCR test and chest CT
  • Patients who had not completed the six minute walk test (6MWT), Borg scales, Short Form-36 and Visual analog scale-pain.
  • Acute COVID-19 patients (patients whose symptoms had started less than one month previous)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Home based cardiopulmonary rehabilitation groupExercise programmeThis was a retrospective study. 43 patients who had home based cardiopulmonary rehabilitation programme between January and July 2023, in our rehabilitation clinic.
Hospital based cardiopulmonary rehabilitation groupExercise programmeThis was a retrospective study. 45 patients who had hospital based cardiopulmonary rehabilitation programme between January and July 2023, in our rehabilitation clinic.
Primary Outcome Measures
NameTimeMethod
Exercise enduranceOne day before exercise programme start and one day later exercise programme ends

Six minutes walk test (All patients walked along a 30-meter-long corridor without obstacles at their normal walking speed, how many meters they walked was noted.)

Secondary Outcome Measures
NameTimeMethod
short form 36One day before exercise programme start and one day later exercise programme ends

A quality-of-life assessment was performed using the Short Form-36, which has 36 items regarding physical function, physical role, emotional role, energy, body pain, mental health, general health, and social function. The scale ranges from 0 (poor health) to 100 (perfect health)

DyspneaOne day before exercise programme start and one day later exercise programme ends

Borg scale were also measured before and after 6MWT for perceived dyspnea (scale range from 0 to 10)

Muscle fatigueOne day before exercise programme start and one day later exercise programme ends

Borg muscle fatigue (scale range from 6 to 20: higher values show more severe symptoms)

Musculoskeletal PainOne day before exercise programme start and one day later exercise programme ends

Visual analog scale-pain was used to measure general body musculoskeletal pain, which was assessed from 0 (no pain) to 10 (worst possible pain)

Trial Locations

Locations (1)

Eskişehir Osmangazi University

🇹🇷

Eskişehir, Odunpazarı, Turkey

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