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临床试验/CTRI/2023/06/053433
CTRI/2023/06/053433尚未招募1 期

A clinical trial to evaluate the efficacy of Shatapushpa churna following Vaman karma and following Basti karma in Artavakshaya w.s.r to Polycystic ovarian diseases

JS Ayurveda Mahavidyalaya1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2023年6月14日最近更新:

试验速览

阶段
1 期
状态
尚未招募
发起方
入组人数
120
试验地点
1
主要终点
patient will get normal menstrual cycle ,Normal ovarian volume and normal follicular growth will be assessed through sonography

研究概览

简要总结

An increasing number of patients with various forms of menstrual irregularities are seen. Prevalence of PCOD in India ranges from 3.7 to 22.5 per cent depending on the population studied and the criteria used for diagnosis1.Of the various lines of treatment available for PCOD, hormonal therapy is the main choice. Hormone therapy may provide excellent results for a short period. But over time it can lead to irreversible metabolic damage. It further depletes the already taxed endocrinal system and puts it to sleep.2 There is no clear correlation of PCOD in Ayurveda classics, but based on symptoms  In artavakshaya menstruation fails to occur at proper time i.e regular monthly cycles do not occur or cycles are delayed or scanty3. Hence based on the symptoms artavakshaya can be correlated with Polycystic ovarian disease. In samprapti main doshik involvement in PCOD is Vata and Kapha. In Ayurveda classics samshodhana and agneya substances are advised as main line of treatment.4 Hence vamana karma is advised as samshodhana karma as it removes saumya (Kapha) substances causing relative increase in agneya constituents and as a consequence increase artava5. Apaana Vayu is the governing factor of the normal physiology of menstruation5. If there is any obstruction in the prakruta movement of apaana vayu, it gets vitiated and affects artava pravritti. In this aspect, Basti chikitsa  is considered to be the best treatment6.The drug Shatapushpa is also indicated for any type of artava kshaya i.e qualitative , quantitative or frequency.7 Hence in the present study,   an attempt is made to compare the effect of Vamana Karma and Basti and Shatapushpa choorna in the management of Artavakshaya w.s.r. to PCOD (Polycystic Ovarain disease).

研究设计

研究类型
Interventional
分配方式
Adaptive randomization, such as minimization
盲法
Not Applicable

入排标准

年龄范围
18.00 Year(s) 至 35.00 Year(s)(—)
性别
Female

入选标准

  • Patients diagnosed with Artava Kshaya.
  • Patients diagnosed with PCOD 3) Patients fit for Vamana karma or Basti karma.

排除标准

  • Patients suffering from Artavakshaya secondary to hypo/hyper thyroidisim, tuberculosis, anemia, congenital adrenal hyperplasia, androgen secreting tumors, functional hypothalamic amenorrhoea, hyperprolactinaemia, any congenital deformity in genital tract.
  • •Patients with cardiac disorders, congenital anomalies of reproductive organs, malignant tumours of reproductive organs, adrenal/pituitary tumours, Cushing Syndrome..
  • •Patients associated with any other severe systemic illness.

结局指标

主要结局

patient will get normal menstrual cycle ,Normal ovarian volume and normal follicular growth will be assessed through sonography

时间窗: 8 weeks

次要结局

  • patients normal mentrual cycle normal follicular growth & normal ovarian volume will be maintained(8weeks)

研究者

发起方
JS Ayurveda Mahavidyalaya
申办方类型
Private medical college

研究点 (1)

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