NCT01317511已完成不适用
Overnight Protein Supply as a Dietary Strategy to Improve Muscle Mass in Elderly.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- Protein synthesis
研究概览
简要总结
Stimulating overnight muscle protein synthesis, might augment muscle hypertrophy, increase mitochondrial mass, and/or improve muscle tissue repair. The goal of this proposal will be to provide further insight into the responsiveness of the muscle protein synthetic machinery to food intake in relation to age.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 80 Years（Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age between 65 and 80 years
- •BMI < 30 kg/m2
排除标准
- •Type 2 diabetic patients
- •Use of medication
- •All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. artrosis, arthritis, spasticity/rigidity, all neurological disorders and paralysis).
- •Use of anticoagulants, blood diseases, allergy for lidocain.
- •Contra indications for the use of a nasogastric tube: high risk of aspiration, gastric stasis, gastro-oesophageal reflux, upper gastrointestinal stricture, nasal injuries and base of skull fractures.
- •Patients suffering from PKU (Phenylketonuria).
结局指标
主要结局
Protein synthesis
时间窗: overnight (12 h)
Overnight protein synthesis
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
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