Protein Supply in Elderly

Not Applicable

Completed

• Conditions: Muscle Synthesis
• Interventions: Dietary Supplement: Protein

• Registration Number: NCT01317511
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

Stimulating overnight muscle protein synthesis, might augment muscle hypertrophy, increase mitochondrial mass, and/or improve muscle tissue repair. The goal of this proposal will be to provide further insight into the responsiveness of the muscle protein synthetic machinery to food intake in relation to age.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06
• Primary Completion: 2010-12
• Study Completion: 2011-02
• Status Verified: 2011-03
• Study First Submitted: 2011-03-16
• Study First Submitted QC: 2011-03-16
• Last Update Submitted: 2011-03-16
• Study First Posted: 2011-03-17
• Last Update Posted: 2011-03-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 16

Inclusion Criteria

• Males
• Age between 65 and 80 years
• BMI < 30 kg/m2

Exclusion Criteria

• Type 2 diabetic patients
• Use of medication
• All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. artrosis, arthritis, spasticity/rigidity, all neurological disorders and paralysis).
• Use of anticoagulants, blood diseases, allergy for lidocain.
• Contra indications for the use of a nasogastric tube: high risk of aspiration, gastric stasis, gastro-oesophageal reflux, upper gastrointestinal stricture, nasal injuries and base of skull fractures.
• Patients suffering from PKU (Phenylketonuria).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Protein	Protein	Protein drink
Placebo	Protein	water

Primary Outcome Measures

Name	Time	Method
Protein synthesis	overnight (12 h)	Overnight protein synthesis

Trial Locations

Locations (1)

Maastricht University Medical Centre; 🇳🇱 Maastricht, Limburg, Netherlands