MedPath

Evidence Based Information Provision to Improve Decision Making After Oesophagogastric Cancer Diagnosis (SOURCE)

Not Applicable
Recruiting
Conditions
Oesophageal Cancer
Gastric Cancer
Interventions
Other: Tool and training
Registration Number
NCT04232735
Lead Sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Brief Summary

The overarching aim of the programme 'Stimulating evidence based, personalized and tailored information provision to improve decision making after oesophagogastric cancer diagnosis' (SOURCE) is to provide oesophagogastric cancer patients at all disease stages with evidence based and personalized information about survival, treatment-related side-effects and/or complications and health related quality of life, tailored to patients' specific information needs, to facilitate informed decision making about treatment and thereby optimize personal care and outcomes.

For this purpose the Source tool and training were designed. The Source tool is a prediction model based website to be used by care givers for informing patients about the outcomes of treatment. The Source training for care givers is designed to learn care givers how to inform patients effectively, especially about the outcomes of treatment.

Detailed Description

The overarching aim of the programme 'Stimulating evidence based, personalized and tailored information provision to improve decision making after oesophagogastric cancer diagnosis' (SOURCE) is to provide oesophagogastric cancer patients at all disease stages with evidence based and personalized information about survival, treatment-related side-effects and/or complications and health related quality of life, tailored to patients' specific information needs, to facilitate informed decision making about treatment and thereby optimize personal care and outcomes.

For this purpose the Source tool and training were designed. The Source tool is a prediction model based website to be used by care givers for informing patients about the outcomes of treatment. The Source training for care givers is designed to learn care givers how to inform patients effectively, especially about the outcomes of treatment.

The primary aim of the SOURCE trial is to investigate the effect of the tool and training on the (numerical) precision of information about outcomes of treatment in the treatment information consultation. Secondary outcomes include: patients' satisfaction, evaluation and knowledge of the information provided by the health care provider, evaluation of the decision made and health related quality of life.

A pragmatic stepped wedge design will be used to test the effect of intervention. 21 health care providers will include 3 patients as control measurements (before intervention) and 3 patients as intervention measurements (after intervention). Participating centers will be divided into geographical subgroups, in which the transition period (in which the intervention will take place) will be spread across time.

All oesophageal and gastric cancer patients scheduled for a treatment information consultation with a participating health care provider are suitable for inclusion and will be approached for participation in the SOURCE study. Measurements include audio recordings of the treatment information consultation and questionnaires filled in by patients and health care providers at different moments in time. Audio recordings will be scored and analyzed based on a study specific coding scheme.

The investigators estimate the physical burden/risk of this study to be negligible.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
126
Inclusion Criteria

Health care providers:

  • Specialist, physician assistant or nurse practitioner in the field of oncology, oncological radiotherapy or oncological surgery who are used to discussing treatment and treatment outcome with patients
  • Informed consent for data collection
  • Three audiorecorded treatment information consultations with oesophageal or gastric cancer patients before the scheduled transition period (control measurements)
  • Three audiorecorded treatment information consultations with oesophageal or gastric cancer patients after the scheduled transition period (intervention measurements) and before the scheduled end date of the study

Patients:

  • Age ≥ 18 years
  • Histological or cytological proof of oesophageal or gastric cancer
  • Informed consent for trial data collection A treatment information consultation with a participating doctor to discuss either curative treatment, first line palliative treatment, and/or best supportive care.
Exclusion Criteria

Health care providers:

  • Less than two control and/or intervention measurements

Patients:

  • Cognitive impairment or insufficient understanding of the Dutch language
  • GIST and smallcell carcinomas.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
InterventionTool and trainingThe Source tool is used by care givers for informing patients about the outcomes of treatment. Prediction models are developed and built in the website in order to generate a personalized prediction of the outcomes: survival, toxicity and/or complications and HRQL. These predictions are visualized in clear and comprehensible graphs with a broad variation of options available for tailoring of the visualizations. In order for care givers to be able to use this tool effectively, we designed the Source training. This communication skills training is comprised of an e-learning, two face-to-face group sessions and an individual booster session. Aside from an instruction video on the navigation within the Source tool, the e-learning consists of theory and tips and tricks on how to inform patients and communicate risks. The face-to-face components of the training are focused on getting the skilled use of the source tool into practice, by receiving personal feedback on the performance.
Primary Outcome Measures
NameTimeMethod
SOURCE observational scalethrough study completion, an average of 1 year

The SOURCE observational scale is developed to primary answer the following question: Does the combination of the tool and the training improve observed (numerical) precision of information about treatment outcomes in clinical consultations? Min. value: 1 Max. value:4 Higher scores mean higher (numerical) precision

Secondary Outcome Measures
NameTimeMethod
State-Trait Anxiety Inventory (STAI)2 weeks vs. baseline

Patients' anxiety

Health care providers' use of visualizations of treatment outcome information measured with SOURCE observational scalethrough study completion, an average of 1 year

Frequency of explicitly showing visualizations treatment outcome information, based on audio tapes Min. value: 0 Max. value: endless Higher values mean more utterances of showing visualizations

Shared Decision Making Questionnaire (SDMQ-9)2 weeks

Patient-reported shared decision making

EORTC QLQ - INFO25 + tailor made items on treatment outcome information2 weeks

Patients' evaluation and knowledge of the information provided by the health care provider

EORTC QLQ-C303 months vs. baseline

Patients' health related quality of life, cancer specific

((Mini-)Mental Adjustment to Cancer scale ((Mini-)MAC)2 weeks vs. baseline

Patients' helplessness/hopelessness + fighting spirit

Health care providers' personalization of treatment outcome information measured with SOURCE observational scalethrough study completion, an average of 1 year

Frequency of explicitly personalizing treatment outcome information, based on audio tapes Min. value: 0 Max. value: endless Higher values mean more utterances of personalization

Decisional Conflict Scale (DCS)2 weeks

Patients' evaluation of the decision made

Health care providers' use of time frames when giving treatment outcome information measured with SOURCE observational scalethrough study completion, an average of 1 year

Presence of time frame when giving treatment outcome information, in utterances coded for the primary outcome Min. value: 0 Max. value: 1 Value 1 means time frame present, value 0 means time frame absent

Continuing professional development (CPD) reaction Questionnairethrough study completion, an average of 1 year

Health care providers' intention to inform patients about treatment outcomes using numbers (effect training only)

Patient Satisfaction Questionnaire (PSQ-5 patient and doctor version)2 weeks

Patient and physician satisfaction with communication and decision making

Trust in the Oncologist Scale (TiOS-sf)2 weeks

Patients' trust in the health care provider

EORTC QLQ-OG253 months vs. baseline

Patients' health related quality of life, gastro-intestinal cancer specific

Duration of consultation in minutes (min.)through study completion, an average of 1 year

Consultation time

Health care providers' tailoring of treatment outcome information measured with SOURCE observational scalethrough study completion, an average of 1 year

Frequency of explicitly tailoring treatment outcome information, based on audio tapes Min. value: 0 Max. value: endless Higher values mean more utterances of tailoring

Treatment outcome category of health care providers' treatment outcome information measured with SOURCE observational scalethrough study completion, an average of 1 year

Treatment outcome category of health care providers' treatment outcome information, in utterances coded for the primary outcome Values: Survival, Health-related Quality of Life, Side effects and complications, Progression of tumor Non-ordinal variable

Person initializing treatment outcome information measured with SOURCE observational scalethrough study completion, an average of 1 year

Person taking the initaitive for the health care provider's treatment outcome information, in utterances coded for the primary outcome Values: Health care provider, Patient Non-ordinal variable

Health care providers' (numerical) precision of treatment outcome information measured with SOURCE observational scale simulated patient consultations (effect intervention)through study completion, an average of 1 year

Health care providers' (numerical) precision of treatment outcome information measured in simulated patient consultations (effect intervention) Min. value: 1 Max. value:4 Higher scores mean higher (numerical) precision

Trial Locations

Locations (12)

Academic Medical Center

🇳🇱

Amsterdam, Noord Holland, Netherlands

Flevoziekenhuis

🇳🇱

Almere, Netherlands

VUmc

🇳🇱

Amsterdam, Netherlands

Radiotherapiegroep

🇳🇱

Arnhem, Netherlands

Rijnstate

🇳🇱

Arnhem, Netherlands

Catherina Ziekenhuis

🇳🇱

Eindhoven, Netherlands

LUMC

🇳🇱

Leiden, Netherlands

Radboud UMC

🇳🇱

Nijmegen, Netherlands

Maastro

🇳🇱

Maastricht, Netherlands

BVI

🇳🇱

Tilburg, Netherlands

ETZ

🇳🇱

Tilburg, Netherlands

UMC Utrecht

🇳🇱

Utrecht, Netherlands

© Copyright 2025. All Rights Reserved by MedPath