NCT06742021招募中不适用
Application of DCE-MRI Based on 4D FreeBreathing in Predicting the Efficacy of Immune and Targeted Therapy in Lung Cancer
Yunnan Cancer Hospital1 个研究点 分布在 1 个国家目标入组 195 人开始时间: 2024年11月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 195
- 试验地点
- 1
- 主要终点
- Tumor treatment response evaluation
研究概览
简要总结
This study aims to address the challenge of predicting the efficacy of targeted and immunotherapy in lung cancer patients. By utilizing two DCE-MRI images-one before treatment and one after one treatment cycle-along with the patients' clinical and pathological information, we aim to achieve accurate prediction of the therapeutic efficacy of targeted and immunotherapy in lung cancer patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Tumor size greater than 2 cm
- •Age between 18 and 75 years
排除标准
- •Presence of MRI contraindications (e.g., metal implants, pacemaker implantation, etc.)
- •Allergy to gadolinium contrast agents
- •Lesions difficult to delineate on images due to conditions such as atelectasis or diffuse lesions
结局指标
主要结局
Tumor treatment response evaluation
时间窗: within one week before treatment and two weeks after treatment completion
This study aims to evaluate tumor treatment response using the RECIST V1.1 criteria, based on CT images taken within one week before treatment and two weeks after treatment completion.
次要结局
未报告次要终点
研究者
研究点 (1)
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