Human Cerenkov Luminescence Imaging of Superficial In-Vivo Tumours after Administration of 18F-FDG

Completed

• Conditions: Cancer; malignant tumours; 10027655

• Registration Number: NL-OMON42215
• Lead Sponsor: ederlands Kanker Instituut

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 12

Inclusion Criteria

Patients, older than 18 years, who will receive and 18F-FDG PET-CT scan and have a superficial tumour, <3 cm from surface, that shows sufficient uptake of 18F-FDG.

Exclusion Criteria

Patient younger than 18 years.
Patients with a melanoma with a high melanin level.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main question is whether we ara able to image the uptake of 18F-FDG in a<br /><br>human tumour, in-vivo, with a stand alone EMCCD camera. The primary study<br /><br>parameter is if we can subjectively distinguish the tumour from the background.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are the signal to noise ratio between the tumour and<br /><br>healthy tissue. With that we take the actual uptake and the depth of the tumour<br /><br>into account.</p><br>