Blastocyst Culture Using Time-lapse in Good Prognosis IVF Patients and Elective Single Embryo Transfer

Dr. Murat Çetinkaya1 site in 1 country64 target enrollmentDecember 2011

ConditionsInfertility

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Infertility
Sponsor: Dr. Murat Çetinkaya
Enrollment: 64
Locations: 1
Primary Endpoint: Blastocyst formation rate
Status: Terminated
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Choosing the best embryo for transfer has become the major challenge in in vitro fertilization (IVF). Morphology alone is obviously not enough and time-lapse incubation has added embryo development kinetics as another selection criterion.

This study was designed to select for the top blastocyst to be replaced, while increasing the pregnancy chance, with the local legislation regulating the number of embryos to be transferred and to establish a morphokinetic standard to be used in our clinical setting.

Registry

clinicaltrials.gov

Start Date

December 2011

End Date

July 2012

Last Updated

13 years ago

Study Type

Interventional

Study Design

Parallel

Sex

Female

Investigators

Sponsor

Dr. Murat Çetinkaya

Responsible Party

Sponsor Investigator

Principal Investigator

Dr. Murat Çetinkaya

R&D Laboratory Manager

Memorial Sisli Hospital, Istanbul

Eligibility Criteria

Inclusion Criteria

•patients in their first or second ART treatment cycle
•no recurrent spontaneous abortions
•age\<35 years
•BMI\<28 kg/m2
•≥8 oocytes retrieved

Exclusion Criteria

•severe endometriosis
•polycystic ovary syndrome
•hydrosalpynx
•uterine pathology
•severe male factor (presenting less than 5 million motile sperm cells in total in the ejaculate)
•very severe morphological sperm defects (mainly globozoospermic or macrocephalic samples)