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Arka dosage form of shweta Aparajita roots in management of Primary Hypothyroidism as add on along with Thyroxine.

Phase 3
Conditions
Health Condition 1: E039- Hypothyroidism, unspecified
Registration Number
CTRI/2024/07/070645
Lead Sponsor
Dr Jayshree Hadke
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients between the age group of 25-50 years & of any Gender.

Patients who are already diagnosed as Primary Hypothyroidism and under Thyroxine

medication and within six months of Diagnosis and newly diagnosed cases.

Patients who are willing and sign the informed consent form.

Exclusion Criteria

Patient suffering from systemic disease like Cardiac Disorder/Diabetes

Mellitus/COPD/TB/HIV/HCV/HBsAg

Immuno-compromised patients.

Pregnancy and lactating mother and Renal insufficiency.

Patient who are known case of Congenital Hypothyroidism, Hypopitutarism, Secondary

Hypothyroidism, Thyroid, Neoplasia & Progressive cases of Myxedema coma.

Any serious medical and psychological condition will be excluded.

Malabsorption disorders

Concomitant use of drugs such as multivitamins, minerals, phenobarbital, phenytoin,

carbamazepine, rifampin, glucocorticoids, warfarin, statins, estrogen, and raloxifene.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Zulewski’s scoring <br/ ><br>ThyQoL <br/ ><br>Anthropometric measuresTimepoint: Clinical Assessment at <br/ ><br>baseline and monthly for 3 <br/ ><br>months. Lab test at base line <br/ ><br>and at the end of 3 months
Secondary Outcome Measures
NameTimeMethod
Free T3 <br/ ><br>Free T4 <br/ ><br>TSH <br/ ><br>Evaluation of TolerabilityTimepoint: Clinical Assessment at <br/ ><br>baseline and monthly for 3 <br/ ><br>months. Lab test at base line <br/ ><br>and at the end of 3 months
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