A comparative clinical study to evaluate the efficacy of Phalatrikadi Kwatha and Vasadi Kashaya in management of Bahupitta Kamala
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- LFTs
研究概览
简要总结
Infections, drugs, alcohol and other dietary and environmental toxins induce structural and functional damage and predispose the liver to vast array of disorders. Bahupitta Kamala.
i.e. Hyperbilirubinemia is a very common disorder found now a days.
In this disease aversion to all desires i.e. food ,exercise ,work, etc. occurs . Bahupitta Kamala is a disease of Raktavaha strotasa, which is given in Ayurvedic texts. In Bahupitta Kamala, the Pitta Dosha of body increases due to Ushna and Tiksna Guna of Pitta. Kamala is mentioned in Ayurvedic texts can be compared with Jaundice
Jaundice is a medical condition characterized by the yellowing of the skin and eyes due to elevated levels of bilirubin in the bloodstream. It can be caused by various factors such as liver disease, hepatitis, alcohol abuse, certain medications, or other underlying health conditions. While conventional medical treatments for jaundice primarily focus on addressing the underlying cause and providing supportive care, traditional systems of medicine, such as Ayurveda, have been explored for their potential efficacy in managing the condition.
The key ingredients in Phalatrikadi Kwatha and Vasadi Kashaya are believed to possess hepatoprotective, antioxidant, anti-inflammatory, and immunomodulatory properties, which could potentially aid in the treatment of jaundice.
While Phalatrikadi Kwatha and Vasadi Kashaya shows promise in traditional use and some preclinical studies, it is essential to note that scientific evidence regarding its efficacy in jaundice is limited. Most of the available studies are preclinical or based on traditional knowledge, and clinical trials are required to establish its effectiveness and safety in the management of jaundice
conducting a comparative study of the efficacy of Phalatrikadi Kwatha and Vasadi Kashaya in Bahupitta Kamala is important to provide scientific evidence, evaluate safety, and support their integration into evidence-based healthcare practices. This research can contribute to the overall understanding and utilization of Ayurvedic formulations for liver disorders, benefiting patients and healthcare providers alike.
Hence Selected this topic for Study
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
入选标准
- •Age limit is from 18 to 60 years irrespective of Gender, Occupation, Religion and Economical condition.
- •Patients having raised serum bilirubin 1.5-15 mg/dl
- •Having signs and symptoms of Bahupitta Kamala 1.Haridra Netra 2.Rakta peet mutrata 3..Daha 4.Haridra Twak 5.Avipaka 6.Dourbalya 7.Aruchi 8.Anutsaha.
排除标准
- •Known cases of HIV infection, Malignancy
- •Patients in hepatic encephalopathy.
- •Serum bilirubin more than 15 mg/dl
- •Pregnant & lactating mother
- •Psychotic patients
- •Congenital Causes -Gilbert’s Syndrome
- •Drug induced hyper bilirubinaemia, Liver abscess.
结局指标
主要结局
LFTs
时间窗: At base line ,15th day ,30th day,45th day
To compare the efficacy of Phalatrikadi Kwatha and Vasadi Kashaya in Bahupitta Kamala
时间窗: At base line ,15th day ,30th day,45th day
次要结局
- To Observe adverse effects of Phalatrikadi Kwatha and Vasadi Kashaya(At base line ,15th day ,30th day,45th day)
研究者
Dr Shruti Suryakant Shelke
MAMs Sumatibhai Shah Ayurved Mahavidyalaya Malwadi Hadapsar Pune