Evaluation of Effect on the heart function of patients with Heart disease following insufflation of Carbon di Oxide into the abdomen for the conduct of laparoscopic gall bladder removal surgery
Not Applicable
- Conditions
- Health Condition 1: K802- Calculus of gallbladder without cholecystitisHealth Condition 2: K80-K87- Disorders of gallbladder, biliary tract and pancreasHealth Condition 3: I519- Heart disease, unspecified
- Registration Number
- CTRI/2019/06/019791
- Lead Sponsor
- Department of Anesthesia PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patient planned for laproscopic cholecystectomy
2.Consent to participation
3.Age 18 to 65 years
4.Patient with echocardiography findings consistent with presence of moderate to severe left ventricular dysfunction for the study group
Exclusion Criteria
1.BMI >35kg/m2
2.Coexisting stenotic valve lesion or right ventricular dysfunction
3.presence of electrcardiographic finding of arrhythmia
4.NYHA 1V physical status
5.End stage hepatic/renal/pulmonary disease
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of effect of pneumoperitoneum on CO and CI in patients with moderate to severe left ventricular dysfunction.Timepoint: All study parameters shall be recorded at the following time points. Pre-induction (T1), 10 minute after induction (T2), when pneumoperitoneum with intra-abdominal (IAP) pressure of 12mm Hg is achieved (T3), 10 minute after reverse Trendelenburg position(T4), 10 minute after deflation of pneumoperitoneum (T5).
- Secondary Outcome Measures
Name Time Method Comparison of effect of pneumoperitoneum on hemodynamic parameters and cardiac function in patients with and without cardiac disease.Timepoint: All study parameters shall be recorded at the following time points. Pre-induction (T1), 10 minute after induction (T2), when pneumoperitoneum with intra-abdominal (IAP) pressure of 12mm Hg is achieved (T3), 10 minute after reverse Trendelenburg position(T4), 10 minute after deflation of pneumoperitoneum (T5).