Factors Influencing the Occurrence and Long-term Survival of Patients With Primary Liver Cancer: A Cohort Study in South China
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 4,000
- 试验地点
- 1
- 主要终点
- Time of Death
研究概览
简要总结
This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer. Basic informations and detailed diagnosis informations (AJCC/TNM stage, MELD score, Child-Pugh score, and BCLC stage) were collected by professional doctors. Clinical outcomes (death, recurrence, and metastasis) will be followed up every two years after therapy.
详细描述
Primary liver cancer (PLC) is highly malignant with high mortality which is particularly popular in China. Many factors are believed to associate with the occurrence and prognosis of liver cancer. This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 18-80 years
- •consistent with primary liver cancer diagnostic criteria
- •first diagnosis (from diagnosis to admission interval of less than a month)
- •did not do any treatment of liver cancer
排除标准
- •refused to participate in this study
- •suffering from more than two kinds of primary tumors
结局指标
主要结局
Time of Death
时间窗: Up to 10 years
The exact death time of each participants will be checked in the government medical records system
次要结局
- Time of recurrence(From date of diagnosis until the date of cancer recurrence or date of death from any cause, whichever came first, assessed up to 10 years)
- Time of metastasis(From date of diagnosis until the date of cancer metastasis or date of death from any cause, whichever came first, assessed up to 10 years)
研究者
Huilian Zhu
Professor
Sun Yat-sen University