Factors Influencing the Occurrence and Long-term Survival of Patients With Primary Liver Cancer: A Cohort Study in South China
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Primary Liver Cancer
- Sponsor
- Huilian Zhu
- Enrollment
- 4000
- Locations
- 1
- Primary Endpoint
- Time of Death
- Status
- Recruiting
- Last Updated
- 8 years ago
Overview
Brief Summary
This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer. Basic informations and detailed diagnosis informations (AJCC/TNM stage, MELD score, Child-Pugh score, and BCLC stage) were collected by professional doctors. Clinical outcomes (death, recurrence, and metastasis) will be followed up every two years after therapy.
Detailed Description
Primary liver cancer (PLC) is highly malignant with high mortality which is particularly popular in China. Many factors are believed to associate with the occurrence and prognosis of liver cancer. This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer.
Investigators
Huilian Zhu
Professor
Sun Yat-sen University
Eligibility Criteria
Inclusion Criteria
- •age 18-80 years
- •consistent with primary liver cancer diagnostic criteria
- •first diagnosis (from diagnosis to admission interval of less than a month)
- •did not do any treatment of liver cancer
Exclusion Criteria
- •refused to participate in this study
- •suffering from more than two kinds of primary tumors
Outcomes
Primary Outcomes
Time of Death
Time Frame: Up to 10 years
The exact death time of each participants will be checked in the government medical records system
Secondary Outcomes
- Time of recurrence(From date of diagnosis until the date of cancer recurrence or date of death from any cause, whichever came first, assessed up to 10 years)
- Time of metastasis(From date of diagnosis until the date of cancer metastasis or date of death from any cause, whichever came first, assessed up to 10 years)