Cytomegalovirus Reactivation in Cancer Patients Receiving Chemotherapy

Completed

• Conditions: Cancer; Cytomegalovirus

• Registration Number: NCT00366717
• Lead Sponsor: Mackay Memorial Hospital

Brief Summary

Cytomegalovirus (CMV) infects most of the world population. This study is to understand if chemotherapy will increase the chance of reactivating CMV. The results may help us in determining when treatment is needed and perhaps Why is it needed.

Detailed Description

Despite CMV reactivation has been clearly described in patients underwent transplantation, this phenomenon has not been studied in patients undergoing chemotherapy. Our purpose is to understand if CMV number increases in monocytic leukocytes during chemotherapy and how is the host response to that changes.

Virus load will be studied by quantitative PCR, host response will be studied by measuring patient's anti-CMV IgG, CMV-associated symptoms, serum IFN-r and TNF-a.

Study Timeline

• Study Start: 2005-06
• Status Verified: 2006-01
• Study Completion: 2006-01
• Study First Submitted: 2006-08-18
• Study First Submitted QC: 2006-08-18
• Last Update Submitted: 2006-08-18
• Study First Posted: 2006-08-21
• Last Update Posted: 2006-08-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• clinical diagnosis of any cancer
• chemotherapy is needed for more than 6 months
• age>20 years old

Exclusion Criteria

• those who do not agree to participate

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Mackay Memorial Hospital; 🇨🇳 Taipei, Taiwan