NCT00366717
Completed
Not Applicable
Cytomegalovirus Reactivation in Cancer Patients Receiving Chemotherapy
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Mackay Memorial Hospital
- Enrollment
- 20
- Locations
- 1
Overview
Brief Summary
Cytomegalovirus (CMV) infects most of the world population. This study is to understand if chemotherapy will increase the chance of reactivating CMV. The results may help us in determining when treatment is needed and perhaps Why is it needed.
Detailed Description
Despite CMV reactivation has been clearly described in patients underwent transplantation, this phenomenon has not been studied in patients undergoing chemotherapy. Our purpose is to understand if CMV number increases in monocytic leukocytes during chemotherapy and how is the host response to that changes.
Virus load will be studied by quantitative PCR, host response will be studied by measuring patient's anti-CMV IgG, CMV-associated symptoms, serum IFN-r and TNF-a.
Study Design
- Study Type
- Observational
- Observational Model
- Defined Population
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 20 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •clinical diagnosis of any cancer
- •chemotherapy is needed for more than 6 months
- •age\>20 years old
Exclusion Criteria
- •those who do not agree to participate
Investigators
Study Sites (1)
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