Effect of intranasal dexmedetomidine on post spinal anaesthesia shivering during Cesarean delivery:A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- TO DETERMINE THE OCCURENCE OF CLINICALLY SIGNIFICANT POST SPINAL ANAESTHESIA SHIVERING
研究概览
简要总结
Dexmedetomidine is a potent, selective alpha2-adrenoceptor agonist and promotes sedation, anxiety reduction, and analgesia without causing respiratory depression.
The administration of intravenous dexmedetomidine has been proved to be an effective measure to treat and prevent post spinal anaesthesia shivering.
This study is about the efficacy of intranasal dexmedetomidine for the control of post spinal anaesthesia shivering in patients undergoing cesarean delivery .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Age between 20-45 years.
- •2.ASA-PS II and III.
- •3.Weight between 45 to 75 kgs.
- •4.Normothermic 36.5 to 37.5 degree C 5.Stable hemodynamics SBP greater than 100mmhg.
排除标准
- •1.Declining to participate or receive spinal anaesthesia.
- •2.Absolute contraindications to spinal anaesthesia.
- •3.Height less than 100 cms.
- •4.Morbid obesity with BMI greater than 40KG/M2 .
- •5.Known allergy to dexmedetomidine or bupivacaine.
- •6.Use of epidural catheter.
- •7.Presence of significant cardiac, liver or renal problems.
结局指标
主要结局
TO DETERMINE THE OCCURENCE OF CLINICALLY SIGNIFICANT POST SPINAL ANAESTHESIA SHIVERING
时间窗: Immediately after spinal anaesthesia, 5,10,15,20,30,45,60 mins and at the end of the surgery.Post operative every 30 mins for 120 mins
次要结局
- GRADE OF SHIVERING(GRADE OF SEDATION)
研究者
Dr.Ponnada Naga Meghana
SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES