Multicentric pilot programme for lung cancer screening

Not Applicable

• Conditions: ung cancer; Cancer

• Registration Number: ISRCTN88299564
• Lead Sponsor: ational Cancer Control Programme (PRONACCAN) of Uruguay

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-02
• Last Update Posted: 13 May 2024
• Study Completion: 2028-05-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

1. Availability of written informed consent
2. Aged 50 to 74 years
3. 5-year lung cancer risk of at least 1.51% (using the Lung Cancer Risk Assessment Tool)
4. No advanced chronic lung diseases
5. No advanced occupational hazard conditions
6. A clinical-functional status allowing the possibility to administer surgical treatment

Exclusion Criteria

1. Second primaries of synchronous and metachronous cancer of both lungs or a combination of lung cancer with cancer of other organs excluding uterine cervix cancer, non-melanoma skin cancer, and lower lip cancer radically treated at least 3 years ago
2. Previous treatment for lung cancer
3. Acute tuberculosis
4. Myocardial infarction, stroke in the case history in the course of the past 6 months before enrolling in the study

Criteria for excluding from the study, based on examination findings:
1. Congestive heart failure, class III or IV according to New York Heart Association (NYHA) classification, unrelated to the neoplastic process
2. Uncontrolled severe hypertension or hypertension with systolic pressure >180 mmHg and/or diastolic pressure >110 mmHg, or orthostatic hypotension
3. A positive test for human immunodeficiency virus (HIV), B or C hepatitis, or lues
4. Mental diseases
5. Chronic alcohol addiction
6. Surd mutism

Administrative causes for exclusion from the study:
1. Kinship relations between the patient and the Centre’s employers
2. The inability of visits/procedure performance and regular medical check-ups
3. Refusal to undergo examination or treatment in the course of the study

Study & Design

• Study Type: Observational
• Study Design: Not specified