Effects of Blood Flow Restriction on Clinical Outcomes in Women With Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Quadriceps muscle strength
研究概览
简要总结
Objective is to compare the effects of routine physical therapy with and without low intensity blood flow restriction on pain and quadriceps muscle strength in women with knee osteoarthritis.
A single blinded randomized controlled trial conducted at Department of Physiotherapy, University of Lahore Teaching Hospital, Defense Road, Lahore.
Total 60 participants were randomly assigned in to two groups, with 30 in each group The intervention group received routine physiotherapy program combined with Low Intensity Blood Flow Restriction Technique (LI-BFR. While control group were treated with only routine physiotherapy.
Dynamometer was used to assess the knee extensor strength while Knee injury and osteoarthritis outcome score was used to record any exacerbation in pain and effects of BFR on activities of daily living. Training load determined 20% of 1RM. Data analysis had done on SPSS version 23.
详细描述
nonparametric test Friedman test was for comparison within the groups and Mann Whitney U test was used for comparison between groups.
Randomization had done through the sealed envelope method. After allocation subjects had received their treatment protocals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 45 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Diagnosed patients of grade II knee osteoarthritis
- •Patient's age 45-65
排除标准
- •Bilateral knee replacement
- •Lower limb surgery in the last six months
- •Diagnosis of inflammatory joint or muscle disease
- •Chest pain during exercise or at rest; or need for supplemental oxygen
- •Pregnancy
- •Any systemic disease
结局指标
主要结局
Quadriceps muscle strength
时间窗: 12 Weeks
dynamometer was used to assess strength
thigh muscle size
时间窗: 12 weeks
measuring tape was used to measure
Pain
时间窗: 12 weeks
pain was measured through NPRS
次要结局
- Activities of daily living(12 weeks)