The effects of perioperative probiotic treatment after colorectal surgery

Phase 3

• Conditions: Condition 1: Malignant diseases of colon. Condition 2: Benign diseases of the colon, rectum, anus and anal canal. Condition 3: Foreign body in colon. Condition 4: Other specified diseases of intestine.; Malignant neoplasm of colon; Benign neoplasm of colon, rectum, anus and anal canal; Foreign body in colon, initial encounter; Other specified diseases of intestine; T18.4XXA

• Registration Number: IRCT20140203016473N9
• Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 18 June 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Need for any elective colorectal surgery
Nurgery is done by an attending surgeon
Good nutritional status

Exclusion Criteria

No consent to enter the study
Small or large bowel obstruction
Anticoagulant consumption
ASA class IV
Inflammatory bowel disease
History of chemotherapy
Transplant recipients
Liver cirrhosis
Antibiotic consumption in the week before surgery
Steroid consumption
Diabetes mellitus
Pregnancy or breastfeeding
Immunodeficiency of any cause

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anastomosis rupture. Timepoint: Daily till 30 days after the operation. Method of measurement: Physical examination.;Surgical site infection. Timepoint: Daily till 30 days after the operation. Method of measurement: Physical examination.;Fascia dehiscence. Timepoint: Daily till 30 days after the operation. Method of measurement: Physical examination.;Pulmonary infection. Timepoint: Daily till 30 days after the operation. Method of measurement: Chest x-ray if clinically indicated.;Urinary infection. Timepoint: Daily till 30 days after the operation. Method of measurement: Urinalysis if clinically indicated.;Total duration of hospital stay. Timepoint: Daily. Method of measurement: Total duration of hospital stay till discharge.;Mortality. Timepoint: Daily. Method of measurement: Report of death by attending physician.