Non-invasive Assessment of Gastrointestinal Transit and Motility in Renal Transplant Recipients Employing a Biomagnetic Technique
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Influence of tacrolimus and cyclosporine on gastrointestinal transit
研究概览
简要总结
Gastrointestinal (GI) complications after renal transplantation are commonly reported as side effects of immunosuppressive agents. Despite this, motility disorders have been scantily studied. Alternating Current Biosusceptometry (ACB) are biomagnetic sensors designed for a wide range of applications. In clinical practice, their non-invasive and radiation free features provide an excellent approach for monitoring of GI transit as alternative to scintigraphy and breath tests. The aim of this study is to examine GI transit and motility of solids in stable renal transplant recipients to determine the potential influence of immunosuppressive therapy on gastrointestinal parameters.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy Volunteer or Renal Transplant Patients
- •Signed informed consent obtained
- •Fasted since midnight
排除标准
- •Subject has known GI related symptoms complaints or GI diseases
- •Subject has cancer or other life threatening diseases or conditions
- •Subject is pregnant
- •Subject has undergone abdominal surgery
- •Drug abuse or alcoholism
- •Subject has cardiac pacemaker
- •Subject takes any medication affecting GI motility
结局指标
主要结局
Influence of tacrolimus and cyclosporine on gastrointestinal transit
时间窗: one year
次要结局
未报告次要终点
研究者
Maria do Carmo Borges
Doctor
Universidade Estadual de Ciências da Saúde de Alagoas