Gastrointestinal Transit and Motility in Renal Transplant Recipients
- Conditions
- Change of Transit or CirculationEffects of Immunosuppressant Therapy
- Registration Number
- NCT01777204
- Lead Sponsor
- Universidade Estadual de Ciências da Saúde de Alagoas
- Brief Summary
Gastrointestinal (GI) complications after renal transplantation are commonly reported as side effects of immunosuppressive agents. Despite this, motility disorders have been scantily studied. Alternating Current Biosusceptometry (ACB) are biomagnetic sensors designed for a wide range of applications. In clinical practice, their non-invasive and radiation free features provide an excellent approach for monitoring of GI transit as alternative to scintigraphy and breath tests. The aim of this study is to examine GI transit and motility of solids in stable renal transplant recipients to determine the potential influence of immunosuppressive therapy on gastrointestinal parameters.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
- Healthy Volunteer or Renal Transplant Patients
- Signed informed consent obtained
- Fasted since midnight
- Subject has known GI related symptoms complaints or GI diseases
- Subject has cancer or other life threatening diseases or conditions
- Subject is pregnant
- Subject has undergone abdominal surgery
- Drug abuse or alcoholism
- Subject has cardiac pacemaker
- Subject takes any medication affecting GI motility
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Influence of tacrolimus and cyclosporine on gastrointestinal transit one year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Universidade Estadual de Ciências da Saúde de Alagoas
🇧🇷Maceio, Alagoas, Brazil