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临床试验/IRCT2015072123282N1
IRCT2015072123282N1已完成未知

Evaluation of the effect of Elaeagnus angustifolia alone and in combination with Boswellia thurifera compared with ibuprofen in patients with knee osteoarthritis

Barij Essence Pharmaceutical Company0 个研究点目标入组 75 人开始时间: 待定最近更新:
适应症

试验速览

阶段
未知
状态
已完成
入组人数
75

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
40 years 至 80 years(—)
性别
All

入选标准

  • age of 40 - 80 years; Osteoarthritis of at least one knee for at least 6 months based on the diagnostic criteria of American College of Rheumatology (ACR); Pain score > 40 mm based on the visual analogue scale (VAS); CRP serum level < 10 mg/dL; LPFI (Lequesne Pain and Function Index) score > 7; Grade 2 or 3 of Kellgren-Laurence scale in knee radiography within the past 6 months
  • Exclusion criteria: Dysfunction of either liver, kidneys, or cardiovascular system or malignancy; Use of intra-articular glucocorticoids within the past 3 months; Use of intra-articular sodium hyaluronate within the past 6 months; Use of systemic glucocorticoids (either oral or parenteral) within the past 3 months; Having other osteoarticular disorders (e.g., rheumatoid arthritis and gout); Uncontrolled hypertension (> 140/90 mm Hg); Increased ESR; Having gastric or duodenal ulcers (based on the medical history); Sensitivity to the intervention drug; Being candidate for arthroplasty surgery; Not use of the intervention drug for more than one week; Knee arthroscopy within the past 3 months; Illiteracy

排除标准

  • 未提供

研究者

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