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Clinical Trials/NCT00416156
NCT00416156CompletedNot Applicable

Effect of Weight Reduction on Inflammatory Markers and Genes Expression in Obese Individuals

Taichung Veterans General Hospital1 site in 1 country25 target enrollmentStarted: May 1, 2005Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
25
Locations
1
Primary Endpoint
Inflammatory responses after weight reduction
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

To investigate whether weight reduction by life style modification for 12 weeks will improve circulating inflammatory markers, adipocytokines as well as gene expression of proinflammatory protein obtained from circulating monocytes from obese individuals.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Single Group
Masking
None

Eligibility Criteria

Ages
20 Years to 70 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Nondiabetes obese individuals with BMI greater than 27 kgs/m2

Exclusion Criteria

  • •Abnormal hepatic, renal and cardiac function

Outcomes

Primary Outcomes

Inflammatory responses after weight reduction

Secondary Outcomes

  • BMI
  • Circulating inflammatory markers
  • Adipocytokines
  • Gene Expression from mononuclear cells

Investigators

Sponsor Class
Other

Study Sites (1)

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