Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Basic Autonomic Nervous System Activity
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Vagus Nerve Stimulation
- Sponsor
- Bahçeşehir University
- Enrollment
- 72
- Locations
- 1
- Primary Endpoint
- Systolic Blood Pressure
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Transcutaneous Auricular Vagus nerve stimulation may be successful in cardiac modulation because of the cardiac connections of the vagal nerve. Therefore, in order to observe the cardiac effects, it was analysed the changes in pulse rate, systolic and diastolic blood pressure after transcutaneous auricular vagus nerve stimulation application.
Detailed Description
Participants were divided into four groups (Figure 1) according to PNS and SNS indexes as Group 1 (PNS index \<-2, SNS index \>+2), Group 2 (PNS index \<-2, SNS index \<+2), Group 3 (PNS index \>-2, SNS index \>+2), Group 4 (PNS index \>-2, SNS index \<+2). Participants were assessed with blood pressure, pulse rate and HRV before and after taVNS stimulation. Sympathetic nervous system (SNS) index and parasympathetic nervous system (PNS) index values were assumed to be between -2 and +2 (95%) in the normal population according to Kubios software, and the grouping method was based on this situation.
Investigators
Alper Percin
Principal Investigator
Bahçeşehir University
Eligibility Criteria
Inclusion Criteria
- •Age between 18 and 40 years old.
- •No previous vagus nerve stimulation
Exclusion Criteria
- •Using of any drug, alcohol or smoking.
- •Pregnancy.
- •Known history of acute or chronic illness.
- •Being in the post or peri-menopausal stage.
Outcomes
Primary Outcomes
Systolic Blood Pressure
Time Frame: Up to 6 Months
The systolic blood pressure of the participants was measured with an electronic blood pressure monitor.
Diastolic Blood Pressure
Time Frame: Up to 6 Months
The diastolic blood pressure of the participants was measured with an electronic blood pressure monitor.
Pulse Rate
Time Frame: Up to 6 Months
The pulse rate of the participants was measured with an electronic blood pressure monitor.