Effect of auricular vagus nerve stimulation in Parkinson disease and freezing of Gait
- Conditions
- Parkinson's disease.Parkinson's disease
- Registration Number
- IRCT20121110011424N6
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 54
Hoehn & Yahr index between 2-3
able to walk 30 meters without help
Has been treated with a stable dose of dopaminergic drugs in the last two months
Able to follow simple verbal commands
The patient can turn 180 degrees at one point
The age of patients should be less than 76 years.
The Montreal cognitive assessment index should be less than 21.
Presence of specific musculoskeletal disorders
Heart problems, especially arrhythmias and having a pacemaker
History of stroke and myocardial infarction
Diabetes and neuropathy
The presence of cognitive, vision and breathing problems that affect the performance of tasks
Neurological disorders other than Parkinson's
Surgery that affects the movement of patients.
The patient needs assistance to walk.
Body mass index above 30
A history of receiving vagus nerve stimulation
Taking anticholinergic drugs or cholinesterase inhibitors
Freezing of Gait for reasons other than Parkinson's
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The improvement of movements and gait problems of parkinsonian patients with freezing. Timepoint: Before intervention and 2 weeks after intervention. Method of measurement: Gate analysis with force plate and motion analyzer and MDS-UPDRS questionnaire.;Adverse effect. Timepoint: 2 weeks after intervention. Method of measurement: Adverse effect form.
- Secondary Outcome Measures
Name Time Method