Acute antidepressant effects and response predictors of wake therapy

Not Applicable

Recruiting

• Conditions: A depressive episode in unipolar depressive disorder or bipolar disorder; unipolar depression, bipolar disorder, depressive episode; D003866, D001714

• Registration Number: JPRN-jRCT1030220427
• Lead Sponsor: Yoshiike Takuya

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-29
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1) Aged 20 years or older
2) Capable to provide informed consent
3) Presenting a depressive episode in the course of depressive disorder or bipolar disorder (DSM-5 criteria)
4) Admitted to our hospital
5) A baseline Hamilton Rating Scale for Depression (17-item) score of 14 or higher

Exclusion Criteria

1) Presenting psychotic features in the depressive episode
2) A score greater than 2 on the suicide item of the Hamilton Rating Score for Depression
3) A score greater than 2 on the agitation item of the Hamilton Rating Score for Depression
4) Severe personality disorder(s)
5) A history of drug or alcohol dependency or abuse within the last six months
6) A history of epilepsy
7) Receiving electroconvulsive therapy, repetitive transcranial magnetic stimulation, or cognitive-behavioral therapy
8) Pregnancy
9) Major medical and neurological disorders

Study & Design

• Study Type: Interventional
• Study Design: Not specified