Verification of acute antidepressant effects of wake therapy for a depressive episode and development of predictors of treatment response

Yoshiike Takuya0 sites60 target enrollmentOctober 29, 2022

Overview

No summary available.

Registry

who.int

Start Date

October 29, 2022

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

Yoshiike Takuya

•1\) Aged 20 years or older
•2\) Capable to provide informed consent
•3\) Presenting a depressive episode in the course of depressive disorder or bipolar disorder (DSM\-5 criteria)
•4\) Admitted to our hospital
•5\) A baseline Hamilton Rating Scale for Depression (17\-item) score of 14 or higher

•1\) Presenting psychotic features in the depressive episode
•2\) A score greater than 2 on the suicide item of the Hamilton Rating Score for Depression
•3\) A score greater than 2 on the agitation item of the Hamilton Rating Score for Depression
•4\) Severe personality disorder(s)
•5\) A history of drug or alcohol dependency or abuse within the last six months
•6\) A history of epilepsy
•7\) Receiving electroconvulsive therapy, repetitive transcranial magnetic stimulation, or cognitive\-behavioral therapy
•8\) Pregnancy
•9\) Major medical and neurological disorders