Prospective feasibility study of individualized dose constraint based radiotherapy treatment planning in patients with gynaecological malignancies (ICON-G) - ICON-G

Tata Medical Center0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年5月27日

试验速览

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•Age > 18 years
•ECOG performance status 0 - 2
•Histologically confirmed malignancy of the uterine cervix, endometrium or the vagina requiring treatment with external beam radiotherapy to:
•The whole pelvis ie. the primary tumor or tumor bed along with the pelvic lymph nodes (including the common iliac nodes).
•The whole pelvis along with the para-aortic nodes - extended field radiotherapy.
•Patients who require postoperative radiotherapy should have undergone a complete oncological surgical procedure and should have indication for adjuvant external beam radiotherapy.
•Deemed suitable for curative intent treatment.
•Absence of distant metastases excluding para-aortic nodes.

•Patients receiving radiotherapy to the vulva. These patients are being excluded as they require treatment in a frog leg position and have a different volume of irradiation.
•Patients who require elective irradiation of the inguinal nodes as these patients will require planning in the frog-leg position also.
•Patients with ovarian malignancies - usually these patients do not undergo adjuvant or curative whole pelvic radiotherapy.
•Patients who require radiotherapy for metastatic disease sites
•Patients planned for re-irradiation to a previously irradiated site.
•Patients who are planned for salvage radiotherapy to the para-aortic region.
•Concurrent illness, including severe infection that may jeopardize the ability of the patient to undergo the procedures outlined in this protocol with reasonable safety
•Serious medical or psychiatric conditions that might limit the ability of the patient to comply with the protocol.

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