Randomized Control Trial Comparing Gastric Emptying Following Infracolic vs Supracolic Gastrojejunostomy After Whipples Pancreaticoduodenectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Gastric Emptying assessed clinically and correlated objectively with liquid and solid emptying of radionucleotide
研究概览
简要总结
Patients undergoing whipples pancreaticoduodenectomy tend to develop delayed gastric emptying.
The study compares two types of anastamosis of stomach to jejunum (supracolic and infracolic) and compares whether it influences the gastric emptying.
The clinical evidence of delayed gastric emptying is correlated with objective evidence of liquid and solid emptying by radionuclide study.
The study also tries to evaluate whether pancreatic leak correlates with delayed gastric emptying
详细描述
METHODOLOGY:
This randomized control trial includes all patients undergoing whipples pancreaticoduodenectomy st Asian Institute of Gastroenterology. All patients were randomized by a closed envelope technique. The envelope was opened after complete resection of the specimen and then allocating the patients into either of the two groups, Group A- Infracolic Gastrojejunostomy, Group B- Supracolic Gastrojejunostomy.
Inclusion Criteria:
- All patients undergoing whipples pancreaticoduodenectomy, who consented for the trial and found to be resectable at surgery.
Exclusion Criteria:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing Whipples procedure
排除标准
- •Unresectable tumors at surgery
- •Postoperative mechanical obstruction
- •Postoperative mortality, where the test could not be done
结局指标
主要结局
Gastric Emptying assessed clinically and correlated objectively with liquid and solid emptying of radionucleotide
时间窗: 30 days after surgery
Gastric emptying in the postoperative period in the form of tolerence of food and removal of ryles tube is assessed. This is correlated with liquid and solid emptying of radionucleotide
次要结局
- Correlation of pancreatic duct leak with gastric emptying(30 days after surgery)