Multicomponent Intervention in Women at Risk of Sarcopenia

Not Applicable

Completed

• Conditions: Grip Strength; Body Composition; Sarcopenia; Gait Speed
• Interventions: Other: Multicomponent intervention of resistance exercises, dancing sessions and nutritional education

• Registration Number: NCT06038500
• Lead Sponsor: Coordinación de Investigación en Salud, Mexico

Brief Summary

The goal of this quasi-experimental pilot study is to evaluate the effect of a multi-component intervention in women between 55 and 75 years old at risk of sarcopenia. The main question it aims to answer are: What is the effect of a multi-component intervention in women at risk of sarcopenia? Participants will twelve women between 55 and 75 years old with risk of sarcopenia, who agreed through written informed consent for participate 12 weeks with 24 sessions included dancing, resistance exercises, and nutritional education. The outcomes were muscle mass, grip strength, gait speed and body composition. The effects were measured before and after the intervention, under a self-controlled design.

Detailed Description

Physical exercise, especially resistance exercise, is one of the best non-pharmacological treatment alternatives due to its multiple health benefits and could be a promoter for the prevention of sarcopenia by delaying muscle atrophy produced by the natural aging process. However, scientific literature shows that this activity when combined with other strategies has a better effect on sarcopenia indicators than alone. Dance is a social activity that is part of the culture and life history of human beings, however, current research has focused on studying the cognitive and visuospatial effects of this activity. It could be an activity with beneficial effects on the physical abilities of the individual since dancing improves flexibility, resistance and balance. However, the study of these two strategies, along with nutritional education has been little studied.

Therefore, a pilot test was proposed with the aim of knowing the possible effect of a multicomponent intervention on muscle, strength, performance, and body composition on women at risk of sarcopenia.

Study Timeline

• Study Start: 2019-06-03
• Primary Completion: 2019-09-27
• Study Completion: 2019-09-27
• Status Verified: 2023-09
• Study First Submitted: 2023-09-08
• Study First Submitted QC: 2023-09-08
• Study First Posted: 2023-09-14
• Last Update Submitted: 2023-09-15
• Last Update Posted: 2023-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 14

Inclusion Criteria

• Positive requested through written informed consent
• Current public health insurance
• Preserved physical and mental capacities (verified through data from the medical record)
• Having a lower grip strength, less or equal to 20.99 kg
• Appendicular skeletal muscle index (ASMI) maintained, greater or equal to 5.5 kg/m^2
• Walking speed greater or equal to 0.8 m/s

Exclusion Criteria

• Bioelectric activity add (osteosynthesis metal systems or devices, pacemakers, defibrillators)
• Alterations of body composition (history of cancer, uncontrolled chronic degenerative diseases, risk of malnutrition, respiratory insufficiency, asthma or chronic obstructive pulmonary disease, hospitalization in the year prior to the study; limitations in carrying out the basic activities of daily living; medical contraindication for physical activity, and or belonging to another physical activity group).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Multicomponent Intervention in only one group of women at Risk of Sarcopenia	Multicomponent intervention of resistance exercises, dancing sessions and nutritional education	Quasi-experimental Pre-test/Post-test design - pilot

Primary Outcome Measures

Name	Time	Method
Grip strength	Baseline measurement and final measurement as the end of the 12 weeks of intervention	Evaluated with the JAMAR Plus+ Patterson Medical® digital dynamometer, using the technique proposed by the American Society of Hand Therapists. It was based on the average among all the attempts done on each hand. The results were obtained in kilograms (kg).
Skeletal muscle mass index (SMI)	Baseline measurement and final measurement as the end of the 12 weeks of intervention	Based on the formula validated by Yamada et al (10.3390/ijerph14070809) for multi-frequency devices using the measurements taken with a TANITA MC 780 (ALM = (0.6947 × (Ht\^2/Z50)) + (-55.24 × (Z250/Z5)) + (-10,940 × (1/Z50)) + 51.33)
Gait speed	Baseline measurement and final measurement as the end of the 12 weeks of intervention	Evaluated with a stopwatch to estimate the time after acceleration and before deceleration for a total distance of 4 meters. The unit of measurement was meters between seconds (m/s).

Secondary Outcome Measures

Name	Time	Method
Anthropometric measurements	Baseline measurement and final measurement as the end of the 12 weeks of intervention	Height, mid-arm, waist, hip, and calf measurements stipulated by the ISAK protocol, all measurements were quantified in centimeters (cm).

Trial Locations

Locations (1)

Maria Claudia Espinel-Bermudez; 🇲🇽 Guadalajara, Jalisco, Mexico