The Effect of Intravenous Fentanyl Prior the End of Surgery on Emergence Agitation in Paediatric Patients After General Anesthesia
Overview
- Phase
- Not Applicable
- Intervention
- fentanyl
- Conditions
- Agitation
- Sponsor
- Prince of Songkla University
- Enrollment
- 144
- Locations
- 1
- Primary Endpoint
- the incidence of emergence agitation
- Status
- Completed
- Last Updated
- 14 years ago
Overview
Brief Summary
The propose of this study is to determine the effect of intravenous fentanyl prior the end of surgery on the incidence and severity of EA in pediatric patient.
Detailed Description
Emergence agitation (EA) is a common self limiting problem after emerging from general anesthesia (GA) especially in pediatric patients. The incidence of EA in Thai population, the incidences of EA 43.2% in pediatric patients aged between 2-9 years. There have been many studies tried to reduce the incidence of EA in various ways such as Preoperative anxiety reduction method and medication. Premedication, Sedative drugs and narcotic drugs were used to reduce the incidence of EA.
Investigators
Ngamjit Pattaravit
Doctor
Prince of Songkla University
Eligibility Criteria
Inclusion Criteria
- •Aged between 2-9 years
- •IPD patient
- •Receiving Chloral hydrate 50mg/kg (BW\<20 kgs)or midazolam 0.1 mg /kg (BW\>20 kgs)Per oral for premedication
- •Scheduled for one kind of these surgeries; Otolaryngology, Ophthalmology, Urology, Orthopedic,General surgery, Plastic surgery and Cardiac catheterization.
Exclusion Criteria
- •ASA physical status IV-V
- •History of drug allergy:thiopental, fentanyl cisatracurium, chloral hydrate and diazepam
Arms & Interventions
fentanyl group
First arm: intervention group. Patient in this group received fentanyl 1 mcg/kg (concentration 10mcg/ml) intravenous route 15 minutes before the end of surgery.
Intervention: fentanyl
controlled group
patient in this group received NSS 0.1 ml/kg 15 minutes before the end of surgery
Intervention: NSS
Outcomes
Primary Outcomes
the incidence of emergence agitation
Time Frame: pt was observed since emerging from anesthesia up to 60 minutes
Secondary Outcomes
- severity of emergence agitation(pt was observed since emerging from anesthesia up to 60 minutes)
- adverse effect from intravenous fentanyl prior the end of surgery(pt was observed since emerging from anesthesia upto 60 minutes)
- post operative pain(pt was observed since emerging from anesthesia up to 60 minutes)