Self-Injury Treatment and Recovery in Veterans

Not Applicable

Recruiting

• Conditions: Self-Injurious Behavior
• Interventions: Behavioral: Treatment for Self-Injurious Behaviors; Other: Treatment As Usual

• Registration Number: NCT05969080
• Lead Sponsor: VA Office of Research and Development

Brief Summary

Nonsuicidal self-injury (NSSI) refers to the intentional destruction of one's own body tissue without suicidal intent and for purposes that are not socially sanctioned. While NSSI has been understudied among Veterans, the lifetime prevalence rate of NSSI in Veterans is approximately three times higher than the general population. Moreover, NSSI is associated with increased risk for violence, psychiatric distress, and marked impairment in psychosocial functioning. Even though NSSI is distinct from suicidal behaviors in several important ways, NSSI remains a strong predictor of a future suicide attempt. The primary goal of this project is to evaluate the treatment and acceptability of a brief intervention for NSSI that aims to reduce psychosocial impairment and NSSI behaviors in Veterans.

Detailed Description

Nonsuicidal self-injury (NSSI) refers to the intentional destruction of one's own body tissue without suicidal intent and for purposes that are not socially sanctioned. While NSSI has been understudied among Veterans, the lifetime prevalence rate of NSSI in Veterans is approximately three times higher than the general population. Moreover, NSSI is associated with increased risk for violence, psychiatric distress, and marked impairment in psychosocial functioning. Even though NSSI is distinct from suicidal behaviors in several important ways, NSSI remains a strong predictor of a future suicide attempt. The primary goal of this project is to evaluate the treatment and acceptability of a brief intervention for NSSI that aims to reduce psychosocial impairment and NSSI behaviors in Veterans. This treatment, known as the Treatment for Self-Injurious Behaviors (T-SIB) incorporates evidence-based approaches to replace NSSI with behaviors that improve psychoso ial functioning. A core component of T-SIB is functional assessment that identifies the antecedents and consequences of NSSI. This project will enhance T-SIB by using ecological momentary assessment (EMA) to conduct NSSI functional assessment in-vivo. EMA reduces retrospective recall bias and can increase engagement with therapeutic goals.

Study Timeline

• Study First Submitted: 2023-07-14
• Study First Submitted QC: 2023-07-28
• Study First Posted: 2023-08-01
• Study Start: 2024-10-15
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-14
• Last Update Posted: 2025-03-19
• Primary Completion: 2027-01-01
• Study Completion: 2027-03-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• 18 years of age or older
• Past service in the United States military
• Nonsuicidal self-injury engagement on 2 occasions in past 30 days
• Fluent in English
• Able to provide voluntary informed consent

Exclusion Criteria

• Lifetime history of psychosis, mania, or hypomania
• Imminent risk for suicide/homicide warranting immediate intervention
• Unable/unwilling to complete study procedures

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
T-SIB	Treatment for Self-Injurious Behaviors	Participants randomized to the Treatment for Self-Injurious Behaviors (T-SIB) condition will receive nine sessions of T-SIB.
Treatment As Usual	Treatment As Usual	Participants randomized to the TAU condition will be provided with referrals to both Durham VA and local community mental health resources and offered a consult for Durham VA mental health services.

Primary Outcome Measures

Name	Time	Method
Feasibility as measured by number of participants enrolled	2 years after study enrollment begins	All participants (N = 40) will need to be enrolled by the end of the second year of the study to consider the recruitment benchmark met.
Feasibility as measured rate of retention	End of treatment, about nine weeks after beginning the study	Retention will be measured by the number of participants who complete at least six T-SIB treatment sessions. This benchmark will be considered meet if at least 2/3 of the 20 participants randomized to T-SIB complete at least 6 treatment sessions.

Secondary Outcome Measures

Name	Time	Method
Number of participants who report satisfaction with the T-SIB treatment	End of treatment, about nine weeks after beginning the study	Participant satisfaction will be measured with the Client Satisfaction Questionnaire (CSQ-8). Total scores on the CSQ-8 range from 8 to 32, which higher scores indicating higher satisfaction. A cut score of 24 will be used such that if the CSQ-8 score exceeds 24, that patient is deemed to have been satisfied with the treatment.

Trial Locations

Locations (1)

Durham VA Medical Center, Durham, NC; 🇺🇸 Durham, North Carolina, United States